Selten M H A, Broekema F I, Zuidema J, van Oeveren W, Bos R R M
Uit de afdeling Kaakchirurgie van het Universitair Medisch Centrum Groningen.
Ned Tijdschr Tandheelkd. 2013 Jul-Aug;120(7-8):378-82.
In this split mouth experiment, the feasibility ofpolyurethane foam as a local hemostatic agent after dental extractions was studied. Ten healthy patients underwent 2 extractions ofa dental element in 1 treatment session. The 10 patients were subsequently randomly divided in a gelatin group and a collagen group. In the gelatin group, a polyurethane foam (PU) was applied in 1 extraction socket, while in the other socket a commercially available gelatin foam was applied. In the collagen group, a PU was applied in 1 socket, and a collagen wadding in the other. All hemostats were removed after 2 minutes, after which the degree of coagulation was measured using a thrombin/antithrombin test and a fibrinogen test. This study suggests that polyurethane foam has hemostatic capacity. Large scale clinical research is needed to confirm this finding, and should indicate whether this hemostatic capacity is clinically relevant.
在这项双侧对照实验中，研究了聚氨酯泡沫作为拔牙后局部止血剂的可行性。10名健康患者在1次治疗过程中接受了2颗牙齿的拔除。随后，这10名患者被随机分为明胶组和胶原组。在明胶组中，在1个拔牙窝中应用聚氨酯泡沫（PU），而在另一个拔牙窝中应用市售明胶海绵。在胶原组中，在1个拔牙窝中应用PU，在另一个拔牙窝中应用胶原棉絮。2分钟后取出所有止血剂，然后使用凝血酶/抗凝血酶试验和纤维蛋白原试验测量凝血程度。本研究表明聚氨酯泡沫具有止血能力。需要进行大规模临床研究以证实这一发现，并应表明这种止血能力是否具有临床相关性。
