Chemical Faculty, Department of Chemical and Process Engineering, Gdansk University of Technology, G. Narutowicza 11/12 Str., 80-233, Gdansk, Poland,
Anal Bioanal Chem. 2013 Oct;405(25):8377-82. doi: 10.1007/s00216-013-7236-z. Epub 2013 Aug 8.
Previous studies have revealed it is possible to separate a high-boiling mixture by gas chromatography in empty fused-silica capillary tubing rather than in columns coated with stationary phase. Chromatographic separation occurs solely on the basis of the different boiling points of the substances separated. The high similarity of such separations to those in classic distillation seems advantageous when gas chromatography is used for simulated distillation. This paper presents results from further research on the separation properties of empty fused silica tubing. The efficiency of this chromatographic system has been examined. The usefulness of such conditions has been studied for simulated distillation, i.e. to determine the boiling-point distribution of complex mixtures, mainly petroleum fractions and products, on the basis of their retention relative to reference substances. The results obtained by use of empty-column gas chromatography (EC-GC) and by use of classical simulated distillation columns have been compared for solutes of different polarity. Studies revealed boiling points determined by EC-GC were more accurate than those obtained by the standard method of simulated distillation.
先前的研究表明，通过在空熔融石英毛细管中而不是在涂有固定相的柱中进行气相色谱，可以分离高沸点混合物。色谱分离仅基于分离物质的不同沸点。当气相色谱用于模拟蒸馏时，这种分离与经典蒸馏的高度相似似乎具有优势。本文介绍了对空熔融石英管分离性能的进一步研究结果。已经检查了这种色谱系统的效率。已经研究了这种条件在模拟蒸馏中的有用性，即根据相对于参比物质的保留来确定复杂混合物（主要是石油馏分和产品）的沸点分布。对不同极性的溶质进行了比较，比较了使用空柱气相色谱（EC-GC）和使用经典模拟蒸馏柱的结果。研究表明，EC-GC 测定的沸点比标准模拟蒸馏法更准确。
