Choudhary Sandeep, Alam Anwer, Dewan Vivek, Yadav Dinesh, Dubey N K
PGIMER & Dr RML Hospital, New Delhi, India.
Clin Pediatr Endocrinol. 2011 Jul;20(3):57-60. doi: 10.1297/cpe.20.57. Epub 2011 Oct 7.
Addison's disease is most commonly due to autoimmune adrenalitis and tuberculosis and refers to primary hypoadrenalism caused by a total or near total destruction or dysfunction of both adrenal cortices. Usual manifestations involve chronic fatigue, muscle weakness, loss of appetite, nausea, vomiting, diarrhea, hypotension and hyperpigmentation of skin. We herein report a case of primary adrenal insufficiency presenting with fever and seizures in an 11-yr-old boy. His symptoms resolved after starting specific therapy. This kind of presentation of Addison's disease is rather unusual.
艾迪生病最常见的病因是自身免疫性肾上腺炎和结核病，指的是双侧肾上腺皮质全部或几乎全部被破坏或功能障碍所导致的原发性肾上腺功能减退。常见表现包括慢性疲劳、肌肉无力、食欲不振、恶心、呕吐、腹泻、低血压以及皮肤色素沉着。我们在此报告一例11岁男孩原发性肾上腺功能不全伴发热和癫痫发作的病例。在开始特异性治疗后，他的症状得到缓解。艾迪生病的这种表现相当不常见。
