• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

伊朗两例原位肝移植(OLT)受者成功妊娠;病例报告两例。

Successful Pregnancies in Two Orthotopic Liver Transplant (OLT) Recipients in Iran; Two Case Reports.

作者信息

Zahra Tayebi, Seyyed Alireza Taqhavi, Shirin Shahbazi

机构信息

Namazi Educational Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

J Reprod Infertil. 2009 Oct;10(3):225-9.

PMID:23926473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3719325/
Abstract

INTRODUCTION

Pregnancy and parenting have been part of human life throughout history and liver transplant recipients are not any exception. This paper reports successful pregnancies in two liver transplant recipients in Iran.

CASE PRESENTATION

The first case was a 34-year old woman who had undergone orthotopic liver transplantation (OLT) at Shiraz Namazi Educational Hospital in 2002. She decided to get pregnant seven years after the operation. During pregnancy, immunosuppressive therapy continued, except Mycophenolate Mofetil which has an absolute contra-indication in pregnancy. The patient was followed up during pregnancy by the transplant team as well as a gynecologist. She faced no significant complications and the liver function was stable during pregnancy. She later underwent a Cesarean section in the 38(th) week of gestation and the newborn was a healthy girl weighing 2480g with an Apgar score of 8 at the time of birth. There were no evidences of prematurity or structural abnormalities in the newborn. The second case was a 31-year old primipara who had received an orthotopic liver transplant (OLT) in Shiraz in 2002. She had a smooth pregnancy without any complications and the newborn was a boy weighing 3100g with Apgar scores of 8 and 10 at the time of birth and 5 minutes thereafter, respectively.

CONCLUSION

As the number of transplant recipients is growing along with the number of recipients who are in their fertility years, it is vital to ensure a proper medical care by a coordinated multidisciplinary team during pregnancy.

摘要

引言

怀孕和为人父母贯穿人类历史,肝移植受者也不例外。本文报告了伊朗两名肝移植受者成功怀孕的案例。

病例介绍

第一个病例是一名34岁女性,2002年在设拉子纳马齐教育医院接受了原位肝移植(OLT)。她在术后七年决定怀孕。孕期继续进行免疫抑制治疗,但停用了在孕期有绝对禁忌证的霉酚酸酯。孕期移植团队和妇科医生对患者进行了随访。她未出现重大并发症,孕期肝功能稳定。她后来在妊娠38周时进行了剖宫产,新生儿是一名健康女婴,出生时体重2480克,阿氏评分8分。新生儿无早产或结构异常迹象。第二个病例是一名31岁初产妇,2002年在设拉子接受了原位肝移植(OLT)。她孕期顺利,无任何并发症,新生儿是一名男婴,出生时体重3100克,出生时阿氏评分8分,出生后5分钟阿氏评分10分。

结论

随着移植受者数量以及处于生育年龄的受者数量不断增加,孕期由多学科协作团队提供恰当医疗护理至关重要。

相似文献

1
Successful Pregnancies in Two Orthotopic Liver Transplant (OLT) Recipients in Iran; Two Case Reports.伊朗两例原位肝移植(OLT)受者成功妊娠;病例报告两例。
J Reprod Infertil. 2009 Oct;10(3):225-9.
2
Successful Pregnancy after a Heart Transplant in Iran: A Case Report.伊朗心脏移植术后成功妊娠:一例报告
J Tehran Heart Cent. 2023 Oct;18(4):294-297. doi: 10.18502/jthc.v18i4.14829.
3
Sirolimus used during pregnancy in a living related renal transplant recipient: a case report.西罗莫司在亲属活体肾移植受者孕期的应用:一例病例报告
Transplant Proc. 2008 Sep;40(7):2446-8. doi: 10.1016/j.transproceed.2008.06.015.
4
Administration of Antithymocyte Globulin (Rabbit) to Treat a Severe, Mixed Rejection Episode in a Pregnant Renal Transplant Recipient.给予抗胸腺细胞球蛋白(兔)治疗妊娠肾移植受者的严重混合性排斥反应发作
Pharmacotherapy. 2016 Apr;36(4):e18-22. doi: 10.1002/phar.1725. Epub 2016 Apr 13.
5
Successful orthotopic liver transplantation and delayed delivery of a healthy newborn in a woman with fulminant hepatic failure during the second trimester of pregnancy.一名在妊娠中期发生暴发性肝衰竭的女性成功进行原位肝移植并顺利分娩出一名健康新生儿。
Ann Hepatol. 2014 Mar-Apr;13(2):288-92.
6
Successful pregnancy after in vitro fertilization in an ABO-incompatible kidney transplant recipient receiving rituximab: a case report.ABO 血型不合的肾移植受者接受利妥昔单抗治疗后体外受精妊娠成功:病例报告。
BMC Nephrol. 2019 Jun 6;20(1):206. doi: 10.1186/s12882-019-1396-9.
7
Pregnancy and orthotopic liver transplantation.妊娠与原位肝移植
Transplant Proc. 2013 Jun;45(5):1966-8. doi: 10.1016/j.transproceed.2013.01.013.
8
Report from the National Transplantation Pregnancy Registry: outcomes of pregnancy after transplantation.美国国家移植妊娠登记处报告:移植后妊娠的结局
Clin Transpl. 2006:57-70.
9
Report from the National Transplantation Pregnancy Registry (NTPR): outcomes of pregnancy after transplantation.国家移植妊娠登记处(NTPR)报告:移植后妊娠的结局
Clin Transpl. 2000:123-34.
10
[Pregnancy after hepatic transplantation. 17 pregnancies].[肝移植后妊娠。17例妊娠]
J Gynecol Obstet Biol Reprod (Paris). 1992;21(6):691-6.

引用本文的文献

1
Update on the Teratogenicity of Maternal Mycophenolate Mofetil.母体霉酚酸酯致畸性的最新情况
J Pediatr Genet. 2015 Jun;4(2):42-55. doi: 10.1055/s-0035-1556743.

本文引用的文献

1
Pregnancy after living-related liver transplantation associated with severe preeclampsia and a review of the literature.活体相关肝移植后妊娠并发重度子痫前期 1 例并文献复习
Arch Gynecol Obstet. 2010 Mar;281(3):423-5. doi: 10.1007/s00404-009-1181-2. Epub 2009 Jul 18.
2
Report from the National Transplantation Pregnancy Registry: outcomes of pregnancy after transplantation.美国国家移植妊娠登记处报告:移植后妊娠的结局
Clin Transpl. 2006:57-70.
3
A successful pregnancy following liver transplantation.
Hepatobiliary Pancreat Dis Int. 2007 Feb;6(1):98-100.
4
Pregnancy outcome after liver transplantation: a single-center experience of 71 pregnancies in 45 recipients.肝移植后的妊娠结局:45例受者71次妊娠的单中心经验
Liver Transpl. 2006 Jul;12(7):1138-43. doi: 10.1002/lt.20810.
5
Report from the National Transplantation Pregnancy Registry (NTPR): outcomes of pregnancy after transplantation.美国国家移植妊娠登记处(NTPR)报告:移植术后妊娠结局
Clin Transpl. 2004:103-14.
6
Pregnancy after liver transplantation: report of 8 new cases and review of the literature.肝移植后妊娠:8例新病例报告及文献综述
Transpl Immunol. 2006 Apr;15(4):297-302. doi: 10.1016/j.trim.2006.01.001. Epub 2006 Feb 9.
7
Outcome of four high-risk pregnancies in female liver transplant recipients on tacrolimus immunosuppression.接受他克莫司免疫抑制治疗的女性肝移植受者的4例高危妊娠结局。
Transplant Proc. 2006 Jan-Feb;38(1):255-7. doi: 10.1016/j.transproceed.2005.12.044.
8
Pregnancy outcome in liver transplant recipients.肝移植受者的妊娠结局
Obstet Gynecol. 2003 Jul;102(1):121-8. doi: 10.1016/s0029-7844(03)00369-7.