Ghorbani Behzad, Madahi Pouran, Shirazi Elham, Ardekani Hooman Sadri, Kamali Koorosh
Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
J Reprod Infertil. 2011 Jan;12(1):33-6.
Recent advances in cancer treatment have resulted in an increased number of cancer survivors. Fertility might be impaired by cancer itself or through gonadal damage as a consequence of radio-chemotherapy. Damages to reproductive organs are seen in minimally upto 30% of cancer patients. The aim of the present study was evaluate the attitude of Iranian oncologists toward fertility preservation.
Thirty oncologists filled an author-designed questionnaire which included five multiple choice questions at Mahak hospital, Tehran in 2009. The data were collected and analyzed by SPSS 11.5 software.
More than half of the oncologists believed that radio-chemotherapy has destructive effects on reproductive organs. This study showed that as high as 67% of the respondants believed fertility preservation should be offered to all patients at risk, but 40% of them insisted that the patients should bring up the topic themselves. Only 46% of the oncologist knew about fertility preservation techniques. The greatest barriers for accepting fertility preservation by the parents of children undergoing cancer treatment were: lack of information (41%), hopelessness from treatment prognosis (33%), fear of delay in starting the treatment (15%) and the priority of child survival (11%).
The specific challenges of counseling are time pressure between diagnosis and start of treatment, little knowledge about fertility preservation both by treating oncologists and parents; therefore a team consisting of oncologists, infertility specialists and social workers is recommended in these settings.
癌症治疗的最新进展使得癌症幸存者数量增加。癌症本身或放化疗导致的性腺损伤可能会损害生育能力。在至少30%的癌症患者中可见生殖器官受损。本研究的目的是评估伊朗肿瘤学家对生育力保存的态度。
2009年,30名肿瘤学家在德黑兰的马哈克医院填写了一份由作者设计的问卷,其中包括5个多项选择题。数据通过SPSS 11.5软件收集和分析。
超过一半的肿瘤学家认为放化疗对生殖器官有破坏作用。该研究表明,高达67%的受访者认为应向所有有风险的患者提供生育力保存,但其中40%的人坚持认为患者应自己提出这个话题。只有46%的肿瘤学家了解生育力保存技术。接受癌症治疗儿童的父母接受生育力保存的最大障碍是:信息缺乏(41%)、对治疗预后绝望(33%)、担心延迟开始治疗(15%)和儿童生存优先(11%)。
咨询的具体挑战在于诊断和开始治疗之间的时间压力、治疗肿瘤学家和父母对生育力保存的了解都很少;因此,在这些情况下,建议由肿瘤学家、不孕不育专家和社会工作者组成一个团队。