Imai Yukinori, Nakazawa Manabu, Ando Satsuki, Sugawara Kayoko, Hamaoka Kazuhiro, Oka Masashi, Mochida Satoshi
Gastroenterology & Hepatology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Saitama, Japan.
J Gastroenterol Hepatol. 2014 Feb;29(2):365-71. doi: 10.1111/jgh.12351.
Balloon-occluded retrograde transvenous obliteration (B-RTO) is recognized as the standard therapy for patients with gastric fundal varices in Japan; however, the procedure is difficult when drainage veins other than the gastrorenal shunt developed. The efficacy and safety of B-RTO using a microballoon catheter for such patients were evaluated.
The subjects were 99 patients with gastric fundal varices who fulfilled the criteria for receiving endoscopic and/or interventional therapies. Among these, 95 patients underwent B-RTO. Of the 95 patients, 14 were treated with the use of microballoon catheters, including nine in whom the left inferior phrenic vein was found as a secondary drainage vein in addition to the gastrorenal shunt, and five in whom a gastrorenal shunt was absent. The B-RTO procedure performed using a microballoon catheter inserted through the left inferior phrenic vein in 13 patients, and through the pericardiophrenic vein in one patient.
The B-RTO procedure using microballoon catheters was successful in 13 of the 14 patients (93%), while in the remaining one patient, multiple drainage veins were visualized on venography. Complete obliteration of the varices was achieved in all the 13 patients by injection of 5% ethanolamine oleate iopamidol at a median volume of 25 mL (range, 11 to 40 mL) through the catheters. None of the patients showed injuries of the drainage veins or any systemic complications.
B-RTO using a microballoon catheter is useful for the treatment of gastric fundal varices in which drainage veins other than the gastrorenal shunt developed.
在日本,球囊闭塞逆行静脉栓塞术(B-RTO)被认为是胃底静脉曲张患者的标准治疗方法;然而,当出现胃肾分流以外的引流静脉时,该手术操作困难。本研究评估了使用微球囊导管对这类患者进行B-RTO的疗效和安全性。
研究对象为99例符合接受内镜和/或介入治疗标准的胃底静脉曲张患者。其中,95例患者接受了B-RTO治疗。在这95例患者中,14例使用微球囊导管进行治疗,其中9例除胃肾分流外还发现左下膈静脉为次要引流静脉,5例无胃肾分流。13例患者通过左下膈静脉插入微球囊导管进行B-RTO手术,1例患者通过心包膈静脉插入微球囊导管进行手术。
14例患者中,13例(93%)使用微球囊导管进行的B-RTO手术成功,而在其余1例患者中,静脉造影显示有多条引流静脉。通过导管注入中位体积为25 mL(范围为11至40 mL)的5%油酸乙醇胺碘帕醇,所有13例患者的静脉曲张均实现完全闭塞。所有患者均未出现引流静脉损伤或任何全身并发症。
使用微球囊导管进行B-RTO对治疗出现胃肾分流以外引流静脉的胃底静脉曲张有效。