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肝移植后门体分流经逆行经颈静脉断流术治疗:中期结果。

Successful retrograde transvenous obliteration for splenorenal shunts after liver ransplantation: Midterm results.

机构信息

Department of Radiology, Tianjin First Center Hospital, Tianjin, China.

出版信息

Turk J Gastroenterol. 2020 Dec;31(12):910-916. doi: 10.5152/tjg.2020.19846.

Abstract

BACKGROUND/AIMS: The objective of this study was to evaluate the use of Amplatzer-assisted retrograde transvenous obliteration (RTO) in patients with splenorenal shunts (SRSs) after orthotopic liver transplantation (OLT).

MATERIALS AND METHODS

From August 2015 to March 2017, 5 patients received RTO at our center because of SRSs after OLT. The clinical features of the patients with SRSs included demographics, donor type, new-onset symptoms, liver function tests, imaging examinations, interventional examinations and treatments, and outcomes. The patients who received RTO were regularly monitored, and data were gathered before and after the procedures and compared using the paired-sample t test.

RESULTS

Percutaneous interventional management was successfully undertaken in all patients, and 5 Amplatzers and 2 stents were also implanted successfully in patients owing to portal vein (PV) stenosis. There were no procedure-related complications in these patients. In all 5 patients with SRSs, 2 weeks after the interventional therapy, the computed tomography findings showed that the splenic renal shunt vein was completely blocked. The mean blood pressure in the donor lateral PV and the mean blood flow velocity of the donor lateral PV after RTO were all improved significantly (p<0.05). It also suggested that all 5 patients with SRSs survived, with the primary graft functioning normally at the final follow-up.

CONCLUSION

Amplatzer-assisted RTO is a safe and effective treatment for SRSs after OLT. Considering the complexity of the diagnosis and treatment of SRSs in liver transplantation, this complication should be taken seriously.

摘要

背景/目的:本研究旨在评估 Amplatzer 辅助逆行经静脉闭塞术(RTO)在肝移植(OLT)后脾肾分流(SRS)患者中的应用。

材料与方法

自 2015 年 8 月至 2017 年 3 月,我院 5 例患者因 OLT 后 SRS 接受 RTO。SRS 患者的临床特征包括人口统计学、供体类型、新发症状、肝功能检查、影像学检查、介入检查和治疗以及结局。接受 RTO 的患者定期接受监测,并使用配对样本 t 检验比较治疗前后的数据。

结果

所有患者均成功实施经皮介入治疗,5 例患者因门静脉(PV)狭窄成功植入 5 个 Amplatzer 和 2 个支架。这些患者均无手术相关并发症。5 例 SRS 患者,介入治疗后 2 周,CT 检查显示脾肾分流静脉完全闭塞。RTO 后供体侧 PV 平均血压和供体侧 PV 平均血流速度均显著改善(p<0.05)。提示 5 例 SRS 患者均存活,最终随访时原移植物功能正常。

结论

Amplatzer 辅助 RTO 是 OLT 后 SRS 的一种安全有效的治疗方法。考虑到肝移植中 SRS 的诊断和治疗的复杂性,应认真对待这一并发症。

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本文引用的文献

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