Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Diabetes Technol Ther. 2013 Aug;15(8):609-18. doi: 10.1089/dia.2013.0177. Epub 2013 Aug 8.
A recent autopsy analysis asserted that incretin drugs have the potential of increasing the risk for pancreatic cancer and for pancreatic neuroendocrine tumors. We examined the Network for Pancreatic Organ Donors with Diabetes (nPOD) database from which that analysis was derived. Our findings raise important questions about the comparability of the two groups of diabetes patients used for the analysis. Our review of the data available on the nPOD Web site and our reading of the earlier article lead us to the conclusion that the data, and the implications of the data, as expressed by the authors of the autopsy analysis are vastly overstated and are a misrepresentation of the information available.
最近的一项尸检分析断言，肠促胰岛素类药物有可能增加患胰腺癌和胰腺神经内分泌肿瘤的风险。我们研究了该分析所源自的糖尿病胰腺器官捐赠者网络（nPOD）数据库。我们的研究结果对用于分析的两组糖尿病患者的可比性提出了重要问题。我们对 nPOD 网站上提供的数据进行了审查，并对较早的文章进行了阅读，我们得出的结论是，尸检分析作者所表达的数据及其影响被大大夸大了，而且是对现有信息的歪曲。
