Pharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstr. 50, CH-4056 Basel, Switzerland.
Expert Rev Clin Pharmacol. 2013 Jul;6(4):413-21. doi: 10.1586/17512433.2013.811829.
Given the importance of high adherence to long-term pharmacotherapy and the growing need to improve medication adherence, choosing the best intervention represents a challenge for healthcare providers. A dose-dispensing service is defined as the repackaging of solid oral medication into dose-dispensing aids by a healthcare provider, mostly in a community pharmacy or hospital pharmacy, in order to assist patients in the management of their polymedication. The personalized dose-dispensing aid organizes individual oral doses according to their prescribed intake schedule throughout the day and the week. This review aims to describe the pros and cons of different dose-dispensing services and technologies, summarizes current evidence and addresses research gaps.
鉴于长期药物治疗的高度依从性的重要性以及提高药物依从性的需求不断增长，为医疗保健提供者选择最佳干预措施是一项挑战。剂量配给服务是指医疗保健提供者将固体口服药物重新包装成剂量配给辅助工具，主要在社区药房或医院药房中，以帮助患者管理其多种药物治疗。个性化剂量配给辅助工具根据患者全天和每周的规定摄入量安排个体口服剂量。本综述旨在描述不同剂量配给服务和技术的优缺点，总结现有证据并解决研究空白。
