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膀胱内维持使用卡介苗治疗浅表性膀胱移行细胞癌:一项回顾性研究。

Maintenance intravesical bacillus calmette-guerin for superficial transitional cell carcinoma of bladder. A retrospective study.

作者信息

Schwalb D M, Addonizio J C, Camilleri J, Choudhury M S, Eshghi M

机构信息

Department of Urology, New York Medical College, Valhalla.

出版信息

Urology. 1990 Sep;36(3):222-5. doi: 10.1016/0090-4295(90)80259-p.

DOI:10.1016/0090-4295(90)80259-p
PMID:2392811
Abstract

Eighteen patients with recurrent and/or multifocal superficial transitional cell carcinoma of the bladder who were rendered tumor-free by transurethral resection and were then treated with either a single or second six-week course of induction Bacillus Calmette-Guerin (BCG) therapy, followed by maintenance therapy, were retrospectively reviewed. A 73 percent complete response rate was achieved in those patients treated prophylactically, while a 70 percent complete response rate was observed in patients treated for carcinoma in situ (CIS) with an average follow-up of twenty-nine months. Maintenance therapy may be warranted in those patients able to tolerate it without significant side effects.

摘要

回顾性分析了18例复发性和/或多灶性膀胱浅表性移行细胞癌患者,这些患者经尿道切除术后肿瘤消失,随后接受了单疗程或第二个六周诱导期卡介苗(BCG)治疗,然后进行维持治疗。预防性治疗的患者完全缓解率为73%,原位癌(CIS)治疗的患者完全缓解率为70%,平均随访29个月。对于能够耐受且无明显副作用的患者,可能需要进行维持治疗。

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