University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Neuroimaging Clin N Am. 2013 Aug;23(3):359-80. doi: 10.1016/j.nic.2012.10.002. Epub 2013 Jan 20.
Magnetic resonance (MR) spectroscopy offers a noninvasive means of assessing in vivo brain metabolites that shed light on cellular concentrations, cell function and dysfunction, cellular energetics, presence of ischemia, and presence of necrosis, among others. Studies obtained at higher field strengths are evolving toward sampling of smaller tissue volumes, greater signal-to-noise ratio, and higher metabolic spatial resolution. This article discusses the usefulness, from the clinical standpoint, of MR spectroscopy in various disorders. However, to be valid and significant the results of MR spectroscopy should always be correlated with their imaging counterparts.
磁共振（MR）波谱提供了一种非侵入性的方法来评估活体脑代谢物，从而揭示细胞浓度、细胞功能和功能障碍、细胞能量学、缺血和坏死的存在等信息。在更高场强下获得的研究正在朝着更小的组织体积、更高的信噪比和更高的代谢空间分辨率的方向发展。本文从临床角度讨论了磁共振波谱在各种疾病中的应用。然而，为了使磁共振波谱的结果具有有效性和重要性，它们应该始终与成像结果相关联。
