Department of Psychiatry, Centro Hospitalar de São João, Porto, Portugal; Department of Obstetrics and Gynecology of Centro Hospitalar São João, Porto, Portugal.
Eur J Obstet Gynecol Reprod Biol. 2013 Nov;171(1):61-6. doi: 10.1016/j.ejogrb.2013.07.034. Epub 2013 Aug 6.
To analyze the psychological impact on levels of anxiety and depression in couples who, confronted with the diagnosis of infertility, propose to carry out ART; to evaluate and compare state-trait anxiety and depression levels in couples undergoing ART treatments for the first time and repeatedly, and to verify gender differences.
In this prospective study in the Medically Assisted Reproduction Unit of the Centro Hospitalar de São João, Porto, Portugal, 89 couples diagnosed with infertility were divided into two groups: (1) couples starting ART for the first time (43), and (2) couples pursuing ART repeatedly (46). Participants completed the Beck Depression Inventory-II (BDI-II) and the State-Trait Anxiety Inventory-Form Y (STAI-Y), prior to their first or subsequent treatment cycle.
Couples pursuing ART for the first time show higher levels of state-anxiety compared to couples who repeatedly carry out ART (p < 0.05). Levels of depression are higher in couples who repeatedly carry out ART (p < 0.05). In both study groups, women and men have higher levels of state-anxiety compared to trait-anxiety (p < 0.05). With respect to depression, there are significant differences between genders in both groups, showing higher values in women compared to men (p < 0.01).
The results show that there is room to tailor psychological interventions for the specific story of each couple, but we emphasize the importance and need for more studies to support these findings.
分析不孕夫妇在接受辅助生殖技术(ART)治疗时,焦虑和抑郁水平的心理影响;评估和比较首次和多次接受 ART 治疗的夫妇的状态-特质焦虑和抑郁水平,并验证性别差异。
本前瞻性研究在葡萄牙波尔图圣若昂医疗生殖中心的生殖医学科进行,将 89 对被诊断为不孕的夫妇分为两组:(1)首次接受 ART 治疗的夫妇(43 对),(2)反复接受 ART 治疗的夫妇(46 对)。在首次或后续治疗周期前,夫妇们完成贝克抑郁量表第二版(BDI-II)和状态-特质焦虑问卷 Y 型(STAI-Y)。
首次接受 ART 治疗的夫妇比反复接受 ART 治疗的夫妇表现出更高的状态焦虑(p<0.05)。反复接受 ART 治疗的夫妇的抑郁水平更高(p<0.05)。在两个研究组中,女性和男性的状态焦虑水平均高于特质焦虑水平(p<0.05)。关于抑郁,两组中都存在明显的性别差异,女性的抑郁水平高于男性(p<0.01)。
结果表明,可以根据每对夫妇的特定情况定制心理干预措施,但我们强调需要更多的研究来支持这些发现。