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酒店研究:居住在边缘住房的社区样本中的多种疾病。

The hotel study: multimorbidity in a community sample living in marginal housing.

出版信息

Am J Psychiatry. 2013 Dec;170(12):1413-22. doi: 10.1176/appi.ajp.2013.12111439.

DOI:10.1176/appi.ajp.2013.12111439
PMID:23929175
Abstract

OBJECTIVE

The health of people living in marginal housing is not well characterized, particularly from the perspective of multimorbid illness. The authors investigated this population in a community sample.

METHOD

A prospective community sample (N=293) of adults living in single-room occupancy hotels was followed for a median of 23.7 months. Assessment included psychiatric and neurological evaluation, multimodal MRI, and viral testing.

RESULTS

Previous homelessness was described in 66.6% of participants. Fifteen deaths occurred during 552 person-years of follow-up. The standardized mortality ratio was 4.83 (95% CI=2.91-8.01). Substance dependence was ubiquitous (95.2%), with 61.7% injection drug use. Psychosis was the most common mental illness (47.4%). A neurological disorder was present in 45.8% of participants, with definite MRI findings in 28.0%. HIV serology was positive in 18.4% of participants, and hepatitis C virus serology in 70.3%. The median number of multimorbid illnesses (from a list of 12) was three. Burden of multimorbidity was significantly correlated with lower role functioning score. Comorbid addiction or physical illness significantly decreased the likelihood of treatment for psychosis but not the likelihood of treatment for opioid dependence or HIV disease. Participants who died during follow-up appeared to have profiles of multimorbidity similar to those of the overall sample.

CONCLUSIONS

This marginally housed cohort had greater than expected mortality and high levels of multimorbidity with adverse associations with role function and likelihood of treatment for psychosis. These findings may guide the development of effective health care delivery in the setting of marginal housing.

摘要

目的

居住在边缘住房中的人的健康状况尚未得到充分描述,尤其是从多种合并症的角度来看。作者在社区样本中研究了这一人群。

方法

对居住在单人间旅馆的成年人进行前瞻性社区样本(N=293)随访,中位数随访时间为 23.7 个月。评估包括精神病学和神经病学评估、多模态 MRI 和病毒检测。

结果

研究对象中有 66.6%的人曾无家可归。在 552 人年的随访期间发生了 15 例死亡。标准化死亡率为 4.83(95%CI=2.91-8.01)。物质依赖普遍存在(95.2%),其中 61.7%为注射吸毒。精神病是最常见的精神疾病(47.4%)。45.8%的参与者存在神经系统疾病,28.0%的参与者存在明确的 MRI 发现。18.4%的参与者 HIV 血清学阳性,70.3%的参与者丙型肝炎病毒血清学阳性。中位数为 3 种(从 12 种疾病列表中)共患疾病。共患成瘾或躯体疾病显著降低了精神病治疗的可能性,但不降低阿片类药物依赖或 HIV 疾病治疗的可能性。随访期间死亡的参与者的共病状况与总体样本相似。

结论

居住在边缘住房的这一群体的死亡率高于预期,且多种合并症的发病率高,与角色功能和精神病治疗的可能性呈负相关。这些发现可能为在边缘住房环境中制定有效的医疗服务提供指导。

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