Ylä-Soininmäki Anne, Moritz Niko, Lassila Lippo V J, Peltola Matti, Aro Hannu T, Vallittu Pekka K
Orthopedic Research Unit, Department of Orthopedic Surgery and Traumatology, University of Turku, 20520, Turku, Finland.
J Mater Sci Mater Med. 2013 Dec;24(12):2683-93. doi: 10.1007/s10856-013-5023-1. Epub 2013 Aug 9.
The aim of this study was to characterize the microstructure and mechanical properties of porous fiber-reinforced composites (FRC). Implants made of the FRC structures are intended for cranial applications. The FRC specimens were prepared by impregnating E-glass fiber sheet with non-resorbable bifunctional bis-phenyl glycidyl dimethacrylate and triethylene glycol dimethacrylate resin matrix. Four groups of porous FRC specimens were prepared with a different amount of resin matrix. Control group contained specimens of fibers, which were bound together with sizing only. Microstructure of the specimens was analyzed using a micro computed tomography (micro-CT) based method. Mechanical properties of the specimens were measured with a tensile test. The amount of resin matrix in the specimens had an effect on the microstructure. Total porosity was 59.5 % (median) in the group with the lowest resin content and 11.2 % (median) in the group with the highest resin content. In control group, total porosity was 94.2 % (median). Correlations with resin content were obtained for all micro-CT based parameters except TbPf. The tensile strength of the composites was 21.3 MPa (median) in the group with the highest resin content and 43.4 MPa (median) in the group with the highest resin content. The tensile strength in control group was 18.9 MPa (median). There were strong correlations between the tensile strength of the specimens and most of the micro-CT based parameters. This experiment suggests that porous FRC structures may have the potential for use in implants for cranial bone reconstructions, provided further relevant in vitro and in vivo tests are performed.
本研究的目的是表征多孔纤维增强复合材料（FRC）的微观结构和力学性能。由FRC结构制成的植入物旨在用于颅骨应用。FRC样本通过用不可吸收的双功能双苯基缩水甘油二甲基丙烯酸酯和三甘醇二甲基丙烯酸酯树脂基体浸渍E玻璃纤维片材制备。制备了四组含有不同量树脂基体的多孔FRC样本。对照组包含仅用浸润剂粘结在一起的纤维样本。使用基于微计算机断层扫描（micro-CT）的方法分析样本的微观结构。通过拉伸试验测量样本的力学性能。样本中树脂基体的量对微观结构有影响。树脂含量最低组的总孔隙率为59.5%（中位数），树脂含量最高组的总孔隙率为11.2%（中位数）。在对照组中，总孔隙率为94.2%（中位数）。除TbPf外，所有基于micro-CT的参数均与树脂含量存在相关性。树脂含量最高组复合材料的拉伸强度为21.3MPa（中位数），树脂含量最高组的拉伸强度为43.4MPa（中位数）。对照组的拉伸强度为18.9MPa（中位数）。样本的拉伸强度与大多数基于micro-CT的参数之间存在强相关性。该实验表明，多孔FRC结构可能有潜力用于颅骨重建植入物，前提是进行进一步相关的体外和体内试验。
