Sartoris A, Succo G, Giordano C, Marcato P, Sorrentino R, Beatrice F, Tavormina P, Boggero R
I Cattedra di Clinica Otorinolaringoiatrica dell'Università di Torino.
Acta Otorhinolaryngol Ital. 1990;10 Suppl 27:19-29.
A study was made to determine how prevalent laryngeal cancer proved to be in 2000 E.N.T. out-patients upon their initial examination. The aim was to ascertain which population was at high risk for laryngeal cancer through the use of computerized analysis of the risk factors. Furthermore, the authors wanted to determine the sensitivity, specificity, predictive value and safety of fiberoptic laryngoscopy as a diagnostic tool to be used in screening. By scanning risk factors for laryngeal cancer, subjects were classified into 3 risk classes: low, medium and high. A total of 71 positive endoscopic tests were found in the high risk class alone. Further diagnostic procedures carried out on these subjects revealed 38 cases of invasive cancer, 43 'in situ' carcinoma and 24 precancerous lesions of the larynx. These data are discussed and the suggestion made that screening for laryngeal cancer only include males over the age of 40. Scanning risk factors such as tobacco and alcohol consumption could also be effective in identifying the high risk groups for laryngeal cancer.
一项研究旨在确定2000名耳鼻喉科门诊患者初诊时喉癌的患病率。目的是通过对危险因素进行计算机分析,确定哪些人群患喉癌的风险较高。此外,作者想确定纤维喉镜作为一种用于筛查的诊断工具的敏感性、特异性、预测价值和安全性。通过扫描喉癌的危险因素,将受试者分为低、中、高3个风险等级。仅在高风险等级中就发现了71例内镜检查呈阳性的病例。对这些受试者进一步进行的诊断程序显示,有38例浸润性癌、43例原位癌和24例喉部癌前病变。对这些数据进行了讨论,并建议喉癌筛查仅包括40岁以上的男性。扫描吸烟和饮酒等危险因素也可能有效地识别喉癌的高风险人群。