Succo G, Beatrice F, Giordano C, Vico F, Sorrentino R, Gandolfo S, Modica R, Sartoris A
I Cattedra di Clinica Otorinolaringoiatrica dell'Università di Torino.
Acta Otorhinolaryngol Ital. 1990;10 Suppl 27:31-40.
A study was made to determine how prevalent oral and oropharyngeal cancer proved to be in 600 E.N.T. out-patients upon their initial examination. The aim was to ascertain which population was at high risk for thys type cancer through the use of computerized analysis of the risk factors. By scoring risk factors for oral and oropharyngeal cancer, subjects were classified into 3 risk classes: low, medium and high. Endoscopy proved positive in 22 cases only in the high risk class. Further diagnostic procedures, performed for all subjects, revealed 16 cases of squamous cell carcinoma, 1 'in situ' carcinoma, and 5 precancerous lesions of the oral cavity and oropharynx. This data is then discussed and the suggestion made that scoring such risk factors as tobacco and alcohol consumption could also be effective in identifying the high risk groups for this disease in a selective screening program.
一项研究旨在确定600名耳鼻喉科门诊患者初诊时口腔和口咽癌的患病率。目的是通过对风险因素进行计算机分析,确定哪些人群患此类癌症的风险较高。通过对口腔和口咽癌的风险因素进行评分,将受试者分为低、中、高三个风险等级。仅在高风险等级的22例患者中,内镜检查呈阳性。对所有受试者进行的进一步诊断程序显示,有16例鳞状细胞癌、1例原位癌以及5例口腔和口咽的癌前病变。随后对这些数据进行了讨论,并提出在选择性筛查项目中,对烟草和酒精消费等风险因素进行评分,也可能有效地识别出该疾病的高风险人群。