Nozawa Y, Abe M, Sakuma H, Ogata M, Haga J, Sakuma H, Wakasa H
1st Department of Pathology, Fukushima Medical College, Japan.
Acta Pathol Jpn. 1990 May;40(5):367-70. doi: 10.1111/j.1440-1827.1990.tb01574.x.
An uncommon case of potentially malignant oncocytoma arising in the pancreatic tail of 54-year-old woman is reported. The tumor was encapsulated and measured 11 x 7 x 6 cm. The tumor cells were uniform in appearance, plump and polyhedral, with distinct finely granular eosinophilic cytoplasm, and were arranged in solid acinar groups. Electron microscopy revealed that the tumor cells contained numerous mitochondria in the cytoplasm. In the present case, the tumor cells showed perineural and small venous invasion in the pancreas and potentially malignant characteristics. However, neither recurrence nor metastasis has been detected 3 years after resection. These findings indicate that the present tumor had apparent low-grade malignancy.
报告了一例发生在一名54岁女性胰尾的潜在恶性嗜酸细胞瘤的罕见病例。肿瘤有包膜，大小为11×7×6厘米。肿瘤细胞外观一致，丰满且呈多面体，有明显的细颗粒状嗜酸性细胞质，排列成实性腺泡状团块。电子显微镜显示肿瘤细胞胞质内含有大量线粒体。在本病例中，肿瘤细胞在胰腺中显示出神经周围和小静脉浸润以及潜在的恶性特征。然而，切除术后3年未检测到复发或转移。这些发现表明本肿瘤具有明显的低级别恶性。
