Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Laryngoscope. 2014 May;124(5):1118-22. doi: 10.1002/lary.24347. Epub 2014 Mar 1.
OBJECTIVES/HYPOTHESIS: To identify patient factors associated with outcomes in critically ill obese patients requiring tracheotomy.
Single-institution, retrospective cohort study.
Charts were reviewed for inpatients admitted to an intensive care unit from 2007 to 2010 with International Classification of Diseases, 9th Revision codes of obesity or morbid obesity and tracheotomy. Variables collected in the dataset include subject age, ethnicity, gender, body mass index, tracheotomy type, patient outcome, chief diagnosis, and medical comorbid conditions. The primary outcomes of interest were tracheotomy type and patient outcome at the time of hospital discharge. Logistic regression models were developed for the probability of each patient outcome using univariate and multivariate models.
One hundred two patients met inclusion criteria. The most common outcome was tracheostomy dependence (49%). Increased mortality was independently significantly associated with pulmonary hypertension (P = .019) and African American ethnicity (P = .045). Increased tracheostomy dependence was significantly associated with obstructive sleep apnea (P = .030). Increased decannulation was significantly associated with percutaneous tracheotomy (P = .016) and Caucasian ethnicity (P < .001).
Obese patients in the intensive care unit who undergo tracheotomy have a high likelihood of remaining tracheostomy dependent at the time of discharge from the hospital. The factors most commonly found to be significantly associated with poor outcomes were open tracheotomy, African American ethnicity, obstructive sleep apnea, and pulmonary hypertension.
目的/假设:确定与需要气管切开的危重症肥胖患者结局相关的患者因素。
单中心回顾性队列研究。
对 2007 年至 2010 年因肥胖或病态肥胖和气管切开术而入住重症监护病房的患者的病历进行了回顾。数据集收集的变量包括患者年龄、种族、性别、体重指数、气管切开术类型、患者结局、主要诊断和合并症。主要关注的结局是气管切开术类型和患者出院时的结局。使用单变量和多变量模型为每种患者结局的概率开发了逻辑回归模型。
102 名患者符合纳入标准。最常见的结局是气管造口依赖(49%)。肺动脉高压(P =.019)和非裔美国人种族(P =.045)与死亡率增加独立显著相关。阻塞性睡眠呼吸暂停(P =.030)与气管造口依赖增加显著相关。经皮气管切开术(P =.016)和白种人种族(P <.001)与拔管增加显著相关。
入住重症监护病房的肥胖患者行气管切开术,出院时仍有很高的气管造口依赖的可能性。与不良结局显著相关的最常见因素是开放性气管切开术、非裔美国人种族、阻塞性睡眠呼吸暂停和肺动脉高压。