Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Münster (Germany) http://www.besenius-group.com; CeNTech, Münster (Germany).
Angew Chem Int Ed Engl. 2013 Sep 16;52(38):10097-101. doi: 10.1002/anie.201303810. Epub 2013 Aug 8.
β-sheet-encoded anionic and cationic dendritic peptide amphiphiles form supramolecular copolymers when self-assembled in a 1:1 feed ratio of the monomers. These ampholytic materials have been designed for on-off polymerization in response to pH triggers. The cooperative supramolecular self-assembly process is switched on at a physiologically relevant pH value and can be switched off by increasing or decreasing the pH value.
β-折叠结构编码的阴离子和阳离子树枝状肽两亲分子在单体 1:1 进料比下自组装时形成超分子共聚物。这些两性材料已被设计用于对 pH 触发的开-关聚合反应。在生理相关的 pH 值下，协同超分子自组装过程被开启，并且可以通过增加或降低 pH 值来关闭。
