生理学。淋巴管在我的静脉里。
Physiology. Lymphatics are in my veins.
机构信息
Yale Cardiovascular Research Center, Yale University School of Medicine, New Haven, CT 06510, USA.
出版信息
Science. 2013 Aug 9;341(6146):622-4. doi: 10.1126/science.1243452.
Abstract
Molecular mechanisms regulating lymphangiogenesis may be exploited as potential treatments for disorders of lymphatic circulation.
摘要
调控淋巴管生成的分子机制可能被用作治疗淋巴循环障碍的潜在方法。
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J Clin Invest. 2013 Jul;123(7):2803-15. doi: 10.1172/JCI60113. Epub 2013 Jun 3.
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Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium.Notch1 在静脉内皮中作为淋巴管内皮细胞分化的负调控因子发挥作用。
Development. 2013 Jun;140(11):2365-76. doi: 10.1242/dev.083865. Epub 2013 Apr 24.
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Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature.游走与远行：脊椎动物淋巴管的发生和形态发生。
Development. 2013 May;140(9):1857-70. doi: 10.1242/dev.089565.
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Endothelial ERK signaling controls lymphatic fate specification.内皮细胞 ERK 信号控制淋巴管命运的指定。
J Clin Invest. 2013 Mar;123(3):1202-15. doi: 10.1172/JCI63034. Epub 2013 Feb 8.
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Blood flow reprograms lymphatic vessels to blood vessels.血流将淋巴管重编程为血管。
J Clin Invest. 2012 Jun;122(6):2006-17. doi: 10.1172/JCI57513. Epub 2012 May 24.
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ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway.ALK1 信号通过与 Notch 通路合作抑制血管生成。
Dev Cell. 2012 Mar 13;22(3):489-500. doi: 10.1016/j.devcel.2012.02.005.
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Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation.机械转导、PROX1 和 FOXC2 合作控制淋巴管瓣膜形成过程中的连接蛋白 37 和钙调神经磷酸酶。
Dev Cell. 2012 Feb 14;22(2):430-45. doi: 10.1016/j.devcel.2011.12.020. Epub 2012 Feb 2.
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