Genetics. The maturing brain methylome.
作者信息
Gabel Harrison W, Greenberg Michael E
机构信息
Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
出版信息
Science. 2013 Aug 9;341(6146):626-7. doi: 10.1126/science.1242671.
Abstract
摘要
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MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.MECP2 与神经系统中富含 5hmC 的活跃基因和可及染色质结合。
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Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.哺乳动物基因组中 5-羟甲基胞嘧啶的碱基分辨率分析。
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5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.5-羟甲基胞嘧啶介导的出生后神经发育和衰老过程中的表观遗传动态变化。
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