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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Science. 2009 May 15;324(5929):929-30. doi: 10.1126/science.1169786. Epub 2009 Apr 16.
2
Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA.
Nucleic Acids Res. 2013 Jul;41(13):6421-9. doi: 10.1093/nar/gkt360. Epub 2013 May 8.
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High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.
J Vis Exp. 2011 Feb 1(48):2661. doi: 10.3791/2661.
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Partial reconstruction of the adult Lurcher cerebellar circuitry by neural grafting.
Neuroscience. 1993 Jul;55(1):1-21. doi: 10.1016/0306-4522(93)90450-t.
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MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.
Cell. 2012 Dec 21;151(7):1417-30. doi: 10.1016/j.cell.2012.11.022.

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Pioneering contribution of Professor Bruce Ames to early development in biochemical aspects of oxidatively generated damage to DNA.
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Genome-Wide 5-Methylcytosine and 5-Hydroxymethylcytosine Signatures Analysis of Plasma Cell-Free DNA in Schizophrenia.
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The role of DNA methylation and demethylation in bladder cancer: a focus on therapeutic strategies.
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Ten-Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy.
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Aberrant histone modifications in pediatric brain tumors.
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本文引用的文献

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Application of a translational profiling approach for the comparative analysis of CNS cell types.
Cell. 2008 Nov 14;135(4):749-62. doi: 10.1016/j.cell.2008.10.029.
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A translational profiling approach for the molecular characterization of CNS cell types.
Cell. 2008 Nov 14;135(4):738-48. doi: 10.1016/j.cell.2008.10.028.
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The colorful history of active DNA demethylation.
Cell. 2008 Jun 27;133(7):1145-8. doi: 10.1016/j.cell.2008.06.009.
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One-electron oxidation of DNA and inflammation processes.
Nat Chem Biol. 2006 Jul;2(7):348-9. doi: 10.1038/nchembio0706-348.
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Nearest-neighbor analysis.
Methods Mol Biol. 2002;200:9-15. doi: 10.1385/1-59259-182-5:009.
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Oxidative damage to 5-methylcytosine in DNA.
Nucleic Acids Res. 1995 Aug 25;23(16):3239-43. doi: 10.1093/nar/23.16.3239.

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