Roy Sudipta, Acharya Rabinarayan, Mandal Narayan C, Barman Soma, Ghosh Ranjan, Roy Rajiv
Department of Dravyaguna, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India.
Anc Sci Life. 2012 Jul;32(1):20-3. doi: 10.4103/0257-7941.113794.
Seed of Guñjā (Abrus precatorius Linn.), a known poisonous drug, is used extensively in various ayurvedic formulations with great therapeutic significance. Ayurveda recommends the administration of Guñjā in diseases like Indralupta (alopecia), Śotha (edema), Kṛmi (helminthes), Kuṣṭha (skin diseases), Kaṇḍu (itching), Prameha (urinary disorders) etc., after being treated with specific Śodhana (purification) procedures.
To assess the antimicrobial action of of raw and Śhodhita (Processed) Guñjā seeds.
Guñjā seeds after being processed with Godugdha (cow's milk), Nimbu swarasa (Lemon juice), Kāñjī (Sour gruel) and water, as the media, were evaluated for its antibacterial effect against clinically important bacterial strains using agar well diffusion method.
Aqueous extracts of raw seeds of Guñjā exert its antibacterial effect on both Gram positive, as well as Gram negative bacteria but none of the Śodhita Guñjā seeds showed any bactericidal effect on any bacterial strains. Chloroform extracts of all the Śodhita Guñjā seed extracts could inhibit bacterial growth but with variations.
The study displayed that chloroform extracts of raw and śodhita samples for bacterial study were much sensitive than the aqueous extracts.
相思子（鸡母珠）种子是一种已知的有毒药物，在各种阿育吠陀配方中被广泛使用，具有重要的治疗意义。阿育吠陀推荐在经过特定的净化程序处理后，将相思子用于治疗诸如因陀罗卢帕（脱发）、索塔（水肿）、克利米（蠕虫病）、库什塔（皮肤病）、坎杜（瘙痒）、普拉梅哈（泌尿系统疾病）等疾病。
评估生相思子和经过净化处理的相思子种子的抗菌作用。
以牛奶、柠檬汁、酸粥和水作为介质对相思子种子进行处理后，采用琼脂扩散法评估其对临床重要细菌菌株的抗菌效果。
生相思子种子的水提取物对革兰氏阳性菌和革兰氏阴性菌均有抗菌作用，但经过净化处理的相思子种子对任何细菌菌株均未显示出杀菌作用。所有经过净化处理的相思子种子提取物的氯仿提取物均可抑制细菌生长，但存在差异。
该研究表明，用于细菌研究的生相思子和经过净化处理的相思子样品的氯仿提取物比水提取物更敏感。
