Tuson Hannah H, Weibel Douglas B
Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.
Soft Matter. 2013 May 14;9(18):4368-4380. doi: 10.1039/C3SM27705D.
The interaction of bacteria with surfaces has important implications in a range of areas, including bioenergy, biofouling, biofilm formation, and the infection of plants and animals. Many of the interactions of bacteria with surfaces produce changes in the expression of genes that influence cell morphology and behavior, including genes essential for motility and surface attachment. Despite the attention that these phenotypes have garnered, the bacterial systems used for sensing and responding to surfaces are still not well understood. An understanding of these mechanisms will guide the development of new classes of materials that inhibit and promote cell growth, and complement studies of the physiology of bacteria in contact with surfaces. Recent studies from a range of fields in science and engineering are poised to guide future investigations in this area. This review summarizes recent studies on bacteria-surface interactions, discusses mechanisms of surface sensing and consequences of cell attachment, provides an overview of surfaces that have been used in bacterial studies, and highlights unanswered questions in this field.
细菌与表面的相互作用在一系列领域具有重要意义，包括生物能源、生物污垢、生物膜形成以及动植物感染。细菌与表面的许多相互作用会导致影响细胞形态和行为的基因表达发生变化，包括对运动性和表面附着至关重要的基因。尽管这些表型已受到关注，但用于感知和响应表面的细菌系统仍未得到充分理解。对这些机制的理解将指导抑制和促进细胞生长的新型材料的开发，并补充对与表面接触的细菌生理学的研究。来自科学和工程领域一系列研究有望为该领域未来的研究提供指导。本综述总结了近期关于细菌-表面相互作用的研究，讨论了表面感知机制和细胞附着的后果，概述了细菌研究中使用的表面，并强调了该领域尚未解答的问题。
