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在莫氏显微外科手术前,肉眼检查、刮除术和皮肤镜检查在确定肿瘤范围方面的比较。

Comparison between examination with naked eye, curretage and dermoscopy in determining tumor extension before Mohs micrographic surgery.

作者信息

Asilian Ali, Momeni Iman

机构信息

Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Adv Biomed Res. 2013 Mar 6;2:2. doi: 10.4103/2277-9175.107961. Print 2013.

Abstract

Mohs micrographic surgery (MMS) is a technique for the treatment of cutaneous malignancies. Subtle determination of tumor margin would end to fewer stages of surgery. Our aim was to compare these three ways for determining tumor extension before initiation of MMS, examination with the naked eye, dermoscopy and curettage. Sixty patients who had basal cell carcinoma (BCC) in head and neck area were randomized in three groups (curettage, dermoscopy and examination with the naked eye). Each group encompassed twenty patients. The total number of resection stages in MMS was recorded for each patient. Demographic data of the patients and the total number of resection stages in MMS were statistically analyzed. Based on analysis of variance (ANOVA) test results, there was no significant difference for total number of stages in statistical point of view between three groups (P value = 0.1). In this research, the Pearson correlation coefficient showed that there is a direct relation between the age and resection stages (r = 0.19, P value = 0.04). The Chi-square test showed no differences between three groups in age, residence and radiotherapy history.

摘要

莫氏显微外科手术(MMS)是一种治疗皮肤恶性肿瘤的技术。精确确定肿瘤边缘可减少手术阶段。我们的目的是比较在开始莫氏显微外科手术前确定肿瘤范围的三种方法,即肉眼检查、皮肤镜检查和刮除术。将60例头颈部基底细胞癌(BCC)患者随机分为三组(刮除术组、皮肤镜检查组和肉眼检查组)。每组20例患者。记录每位患者莫氏显微外科手术的切除阶段总数。对患者的人口统计学数据和莫氏显微外科手术的切除阶段总数进行统计学分析。基于方差分析(ANOVA)测试结果,从统计学角度来看,三组之间的阶段总数没有显著差异(P值 = 0.1)。在本研究中,皮尔逊相关系数表明年龄与切除阶段之间存在直接关系(r = 0.19,P值 = 0.04)。卡方检验显示三组在年龄、居住地和放疗史方面没有差异。

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