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数字皮肤镜检测在头颈部浸润性/硬斑病样型基底细胞癌传统手术切除中的应用价值。

Usefulness of margin detection by digital dermoscopy in the traditional surgical excision of basal cell carcinomas of the head and neck including infiltrative/morpheaform type.

机构信息

Dermatological Surgery, Centro Ortopedico di Quadrante Hospital, Omegna, Italy.

出版信息

J Dermatol. 2012 Apr;39(4):326-30. doi: 10.1111/j.1346-8138.2011.01449.x. Epub 2011 Dec 13.

DOI:10.1111/j.1346-8138.2011.01449.x
PMID:22150641
Abstract

Incomplete or suboptimal surgical excision of basal cell carcinoma of the head and neck is a relatively frequent occurrence. Methods of preoperative assessment of tumoral margins are therefore of paramount importance. The aim of this study was to compare the preoperative evaluation of margins with digital dermoscopy and clinical definition. One hundred and 12 patients with histologically confirmed basal cell carcinoma were selected for surgical excision. Subsequently, the margin of excision was determined by either clinical (45 patients) or dermoscopic evaluation (67 patients). After pre-surgical clinical evaluation, 22% of histological specimens of excised basal cell carcinoma showed suboptimal margins of excision. Pre-surgical dermoscopic evaluation had only 7% suboptimal excision. Preoperative digital dermoscopy is a better method to determine tumoral margins than clinical evaluation alone. Indeed, preoperative digital dermoscopy is an effective, simple, non-invasive procedure for the pre-surgical determination of margins.

摘要

头颈部基底细胞癌手术切除不完整或不彻底的情况较为常见。因此,术前评估肿瘤边缘的方法至关重要。本研究旨在比较数字皮肤镜和临床定义术前评估边缘的效果。121 例经组织学证实的基底细胞癌患者被选行手术切除。随后,通过临床(45 例)或皮肤镜评估(67 例)确定切除边缘。术前临床评估后,22%的切除基底细胞癌组织学标本显示切除边缘不充分。术前皮肤镜评估仅有 7%的切除边缘不充分。术前数字皮肤镜检查是一种比单纯临床评估更好的确定肿瘤边缘的方法。事实上,术前数字皮肤镜检查是一种有效、简单、非侵入性的术前确定边缘的方法。

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