Yu Tian-Shui, Ling Yue, Guan Da-Wei
Key Laboratory of Evidence Science, Ministry of Education, China University of Political Science and Law, Beijing 100040, China.
Fa Yi Xue Za Zhi. 2013 Apr;29(2):140-3.
The myofibroblasts have dual characteristics of smooth muscle cells and fibroblasts. In repairing tissular wound, myofibroblasts are involved in fibrogenesis and remodeling the extracellular matrix of the fibrotic cascades reaction. The review describes the morphological characteristics and biological behaviors of myofibroblasts and the application of skin wound age determination, which may provide reference for research in forensic medicine.
肌成纤维细胞具有平滑肌细胞和成纤维细胞的双重特征。在组织创伤修复过程中,肌成纤维细胞参与纤维化形成以及纤维化级联反应中细胞外基质的重塑。本文综述了肌成纤维细胞的形态学特征、生物学行为以及在皮肤伤口年龄判定中的应用,可为法医学研究提供参考。