Department of Chemical and Biomolecular Engineering and ‡Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104, United States.
Nano Lett. 2013 Sep 11;13(9):4449-55. doi: 10.1021/nl4023308. Epub 2013 Aug 16.
Responsive free-standing films of gold nanoparticles are fabricated by a new approach combining the programmable DNA-directed self-assembly and the layer-by-layer (LbL) thin film fabrication technique. This approach allows for the assembly of multidomain nanoparticle films with each domain possessing distinct properties in response to external stimuli, which is essential for the formation of dynamic nanostructures. Large area free-standing films of DNA-modified gold particles are fabricated by the selective melting of a sacrificial nanoparticle domain, taking advantage of the unique sharp melting transition of DNA-modified gold nanoparticles. Furthermore, we show that released multidomain films can be designed to further split into multiple intact daughter films in a precisely controlled manner, demonstrating that this new approach provides a powerful means to fabricate free-standing nanoparticle films that are capable of programmable transformation.
通过结合可编程 DNA 指导的自组装和层层（LbL）薄膜制造技术，制备了响应性独立金纳米粒子薄膜。该方法允许组装具有各域具有不同性质的多域纳米粒子薄膜，以响应外部刺激，这对于形成动态纳米结构至关重要。通过利用 DNA 修饰金纳米粒子的独特尖锐熔融转变，通过选择性熔融牺牲纳米粒子域，制备了大面积的 DNA 修饰金粒子的独立薄膜。此外，我们表明，释放的多域膜可以被设计成以精确控制的方式进一步分裂成多个完整的子膜，证明这种新方法提供了一种制造能够进行可编程转化的独立纳米粒子膜的强大手段。
