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[最严重烧伤患者急性吸入性损伤的宏观和微观表现的预后意义]

[Prognostic significance of macroscopic and microscopic findings in acute inhalation damage in the most severely burned patients].

作者信息

Barth J, Möllmann H W, Mathey H, Müller F E, Müller K M

机构信息

Medizinische Klinik und Poliklinik, Ruhr-Universität Bochum.

出版信息

Anasth Intensivther Notfallmed. 1990 Jun;25(3):222-7.

PMID:2393078
Abstract

The bronchoscopic examination of the upper respiratory tract is thought to be of major value recognizing and determining the severity of an inhalation injury in burn patients. From clinical observation however it can be questioned if the initial bronchoscopic aspect has indeed any prognostic significance concerning soon or later developing pulmonary complications in those patients. In 15 burn patients with inhalation injury the endoscopically evident lesions of the respiratory tract were classified and documented by photography. Additionally bronchus biopsies for histological examination were taken from different levels of the bronchus tree and a bronchoalveolar lavage (BAL) was performed to gather lung cells of peripheral lung areas. Summarizing the results no firm relations between macroscopically classified degrees of respiratory damage and histopathological diagnosed destructions were found; patients, however, whose differentiation of BAL cells showed an extreme neutrophilia developed progressive lung insufficiency (ARDS) a few days later.

摘要

上呼吸道的支气管镜检查被认为对于识别和确定烧伤患者吸入性损伤的严重程度具有重要价值。然而,从临床观察来看,对于这些患者早期支气管镜检查的表现是否真的对其随后发生肺部并发症具有任何预后意义,仍存在疑问。对15例有吸入性损伤的烧伤患者,通过内镜观察对呼吸道明显病变进行分类,并拍照记录。此外,从支气管树的不同层面取支气管组织进行组织学检查,并进行支气管肺泡灌洗(BAL)以收集外周肺区域的肺细胞。总结结果发现,宏观分类的呼吸道损伤程度与组织病理学诊断的破坏之间未发现确切关联;然而,支气管肺泡灌洗细胞分化显示极度中性粒细胞增多的患者,几天后出现了进行性肺功能不全(ARDS)。

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