Khan Mohammad Noman, Khan Taseer Ahmed, Ahmed Zulfiqar
Department of Physiology, University of Karachi, Karachi, Pakistan.
J Coll Physicians Surg Pak. 2013 Aug;23(8):590-2.
Discrepancies in blood typing is one of the major reasons in eliciting a transfusion reaction. These discrepancies can be avoided through detailed analysis for the blood typing. Here, we report a subgroup of blood group type-B in the ABO system. Donor's blood was analyzed by employing commercial antisera for blood grouping. The results of forward (known antisera) and reverse (known antigen) reaction were not complimentary. A detailed analysis using the standard protocols by American Association of Blood Banking revealed the blood type as a variant of blood group-B instead of blood group-O. This is suggestive of the fact that blood group typing should be performed with extreme care and any divergence, if identified, should be properly resolved to avoid transfusion reactions. Moreover, a major study to determine the blood group variants in Pakistani population is needed.
血型不符是引发输血反应的主要原因之一。通过对血型进行详细分析可以避免这些不符情况。在此，我们报告ABO系统中B血型的一个亚组。使用商业抗血清对献血者血液进行血型分析。正向（已知抗血清）和反向（已知抗原）反应的结果并不相符。采用美国血库协会的标准方案进行详细分析后，发现该血型是B血型的一个变体，而非O血型。这表明血型鉴定应极其谨慎，若发现任何差异，都应妥善解决以避免输血反应。此外，有必要开展一项关于确定巴基斯坦人群血型变体的重大研究。
