Department of Surgery, The University of Virginia, Charlottesville, VA, USA.
J Pediatr Surg. 2013 Aug;48(8):1650-6. doi: 10.1016/j.jpedsurg.2013.01.043.
The purpose of this study was to examine risk-adjusted associations between race and gender on postoperative morbidity, mortality, and resource utilization in pediatric surgical patients within the United States.
101,083 pediatric surgical patients were evaluated using the U.S. national KID Inpatient Database (2003 and 2006): appendectomy (81.2%), pyloromyotomy (9.8%), intussusception (6.2%), decortication (1.9%), congenital diaphragmatic hernia repair (0.7%), and colonic resection for Hirschsprung's disease (0.2%). Patients were stratified according to gender (male: 63.1%, n=63,783) and race: white (n=58,711), Hispanic (n=26,118), black (n=9,103), Asian (n=1,582), Native American (n=474), and other (n=5,096). Multivariable logistic regression modeling was utilized to evaluate risk-adjusted associations between race, gender, and outcomes.
After risk adjustment, race was independently associated with in-hospital death (p=0.02), with an increased risk for black children. Gender was not associated with mortality (p=0.77). Postoperative morbidity was significantly associated with gender (p<0.001) and race (p=0.01). Gender (p=0.003) and race (p<0.001) were further associated with increased hospital length of stay. Importantly, these results were dependent on operation type.
Race and gender significantly affect postoperative outcomes following pediatric surgery. Black patients are at disproportionate risk for postoperative mortality, while black and Hispanic patients have increased morbidity and hospital resource utilization. While gender does not affect mortality, gender is a determinant of both postoperative morbidity and increased resource utilization.
本研究旨在检验美国儿科手术患者种族和性别与术后发病率、死亡率和资源利用之间的风险调整关联。
使用美国国家儿童住院数据库(2003 年和 2006 年)评估了 101083 例儿科手术患者:阑尾切除术(81.2%)、幽门肌切开术(9.8%)、肠套叠(6.2%)、去皮质术(1.9%)、先天性膈疝修补术(0.7%)和先天性巨结肠的结肠切除术(0.2%)。根据性别(男性:63.1%,n=63783)和种族:白人(n=58711)、西班牙裔(n=26118)、黑人(n=9103)、亚洲人(n=1582)、美洲原住民(n=474)和其他(n=5096)对患者进行分层。利用多变量逻辑回归模型评估种族、性别与结局之间的风险调整关联。
风险调整后,种族与院内死亡独立相关(p=0.02),黑人儿童的死亡风险增加。性别与死亡率无关(p=0.77)。术后发病率与性别(p<0.001)和种族(p=0.01)显著相关。性别(p=0.003)和种族(p<0.001)与住院时间延长进一步相关。重要的是,这些结果取决于手术类型。
种族和性别显著影响儿科手术后的结局。黑人患者术后死亡率过高,而黑人和西班牙裔患者发病率和医院资源利用率增加。虽然性别不影响死亡率,但性别是术后发病率和增加资源利用率的决定因素。