Hasegawa Kohei, Tsugawa Yusuke, Brown David F M, Mansbach Jonathan M, Camargo Carlos A
From the *Massachusetts General Hospital; †Harvard Medical School; ‡Beth Israel Deaconess Medical Center, Boston, MA; §Center for Clinical Epidemiology of St. Luke's Life Science Institute, Tokyo, Japan; and ¶Boston Children's Hospital, Boston, MA.
Pediatr Infect Dis J. 2014 Jan;33(1):11-8. doi: 10.1097/INF.0b013e3182a5f324.
To examine temporal trends in emergency departments (EDs) visits for bronchiolitis among US children between 2006 and 2010.
Serial, cross-sectional analysis of the Nationwide Emergency Department Sample, a nationally representative sample of ED patients. We used International Classification of Diseases, Ninth Revision, Clinical Modification code 466.1 to identify children <2 years of age with bronchiolitis. Primary outcome measures were rate of bronchiolitis ED visits, hospital admission rate and ED charges.
Between 2006 and 2010, weighted national discharge data included 1,435,110 ED visits with bronchiolitis. There was a modest increase in the rate of bronchiolitis ED visits, from 35.6 to 36.3 per 1000 person-years (2% increase; Ptrend = 0.008), due to increases in the ED visit rate among children from 12 months to 23 months (24% increase;Ptrend < 0.001). By contrast, there was a significant decline in the ED visit rate among infants (4% decrease; Ptrend < 0.001). Although unadjusted admission rate did not change between 2006 and 2010 (26% in both years), admission rate declined significantly after adjusting for potential patient- and ED-level confounders (adjusted odds ratio for comparison of 2010 with 2006, 0.84; 95% confidence interval: 0.76-0.93; P < 0.001). Nationwide ED charges for bronchiolitis increased from $337 million to $389 million (16% increase; Ptrend < 0.001), adjusted for inflation. This increase was driven by a rise in geometric mean of ED charges per case from $887 to $1059 (19% increase; Ptrend < 0.001).
Between 2006 and 2010, we found a divergent temporal trend in the rate of bronchiolitis ED visits by age group. Despite a significant increase in associated ED charges, ED-associated hospital admission rates for bronchiolitis significantly decreased over this same period.
研究2006年至2010年间美国儿童因细支气管炎前往急诊科就诊的时间趋势。
对全国急诊科样本进行系列横断面分析,该样本是具有全国代表性的急诊科患者样本。我们使用国际疾病分类第九版临床修订本代码466.1来识别2岁以下患有细支气管炎的儿童。主要结局指标为细支气管炎急诊就诊率、住院率和急诊费用。
2006年至2010年间,加权全国出院数据包括1435110例因细支气管炎的急诊就诊。细支气管炎急诊就诊率略有上升,从每1000人年35.6次增至36.3次(增长2%;P趋势=0.008),这是由于12个月至23个月儿童的急诊就诊率上升(增长24%;P趋势<0.001)。相比之下,婴儿的急诊就诊率显著下降(下降4%;P趋势<0.001)。尽管2006年至2010年间未调整的住院率没有变化(两年均为26%),但在对潜在的患者和急诊科层面的混杂因素进行调整后,住院率显著下降(2010年与2006年比较的调整比值比为0.84;95%置信区间:0.76 - 0.93;P<0.001)。经通胀调整后,全国因细支气管炎的急诊费用从3.37亿美元增至3.89亿美元(增长16%;P趋势<0.001)。这一增长是由每例急诊费用的几何平均数从887美元升至1059美元推动的(增长19%;P趋势<0.001)。
2006年至2010年间,我们发现不同年龄组因细支气管炎的急诊就诊率呈现出不同的时间趋势。尽管相关急诊费用显著增加,但同期因细支气管炎的急诊相关住院率显著下降。