The Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts, USA.
Sanofi, Swiftwater, Pennsylvania, USA.
J Infect Dis. 2022 Aug 15;226(Suppl 2):S225-S235. doi: 10.1093/infdis/jiac172.
Limited data are available on the economic costs of respiratory syncytial virus (RSV) infections among infants and young children in the United States.
We performed a systematic literature review of 10 key databases to identify studies published between 1 January 2014 and 2 August 2021 that reported RSV-related costs in US children aged 0-59 months. Costs were extracted and a systematic analysis was performed.
Seventeen studies were included. Although an RSV hospitalization (RSVH) of an extremely premature infant costs 5.6 times that of a full-term infant ($10 214), full-term infants accounted for 82% of RSVHs and 70% of RSVH costs. Medicaid-insured infants were 91% more likely than commercially insured infants to be hospitalized for RSV treatment in their first year of life. Medicaid financed 61% of infant RSVHs. Paying 32% less per hospitalization than commercial insurance, Medicaid paid 51% of infant RSVH costs. Infants' RSV treatment costs $709.6 million annually, representing $187 per overall birth and $227 per publicly funded birth.
Public sources pay for more than half of infants' RSV medical costs, constituting the highest rate of RSVHs and the highest expenditure per birth. Full-term infants are the predominant source of infant RSVHs and costs.
关于美国婴幼儿呼吸道合胞病毒（RSV）感染的经济成本，可用数据有限。
我们对 10 个主要数据库进行了系统文献回顾，以确定 2014 年 1 月 1 日至 2021 年 8 月 2 日期间发表的报告美国 0-59 月龄儿童与 RSV 相关的费用的研究。提取费用并进行系统分析。
共纳入 17 项研究。虽然一名极度早产儿的 RSV 住院费用（RSVH）是足月婴儿的 5.6 倍（10214 美元），但足月婴儿占 RSVH 的 82%和 RSVH 费用的 70%。在生命的第一年，与商业保险婴儿相比，医疗补助保险的婴儿因 RSV 治疗而住院的可能性高 91%。医疗补助计划为 61%的婴儿 RSVH 提供资金。医疗补助计划每住院治疗支付的费用比商业保险低 32%，但支付了婴儿 RSVH 费用的 51%。婴儿的 RSV 治疗费用每年 7.096 亿美元，占总出生人数的 187 美元，占公共资助出生人数的 227 美元。
公共资金支付了超过一半的婴儿 RSV 医疗费用，构成了 RSVH 发生率最高和每出生费用最高的群体。足月婴儿是 RSVH 和费用的主要来源。
