Karrenberg R, Stober H D
Abteilung für Anästhesiologie und Intensivtherapie, St. Hedwig-Krankenhaus, Berlin.
Anaesthesiol Reanim. 1990;15(3):181-7.
A report is given on 2 patients with postoperative liver and kidney insufficiency who showed a hereditary fructose intolerance (HFI) after the infusion of fructose and sorbitol. The pathophysiological and clinical signs of this rare disease are described. Since irreversible organ damage occurs already after the infusion of more than 30 to 40 grams fructose or sorbitol, every therapy is questionable. Therefore, prophylactic measures are important in infusion therapy. Particularly in emergency patients and during the preanaesthetic investigation of patients, HFI must be taken into account in adults.
报告了2例术后出现肝肾不全的患者,他们在输注果糖和山梨醇后表现出遗传性果糖不耐受(HFI)。描述了这种罕见疾病的病理生理和临床体征。由于输注超过30至40克果糖或山梨醇后就会发生不可逆的器官损伤,因此每种治疗方法都存在疑问。因此,预防措施在输液治疗中很重要。特别是在急诊患者以及患者麻醉前检查期间,成人必须考虑到HFI。