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[从神经麻醉角度对成年期遗传性果糖不耐受致死病例报告的批判性评论]

[Critical comments on reports of fatalities in hereditary fructose intolerance in adulthood from the viewpoint of neuroanesthesia].

作者信息

Panning B, Piepenbrock S

机构信息

Abteilung Anästhesiologie II, Medizinische Hochschule Hannover.

出版信息

Anasth Intensivther Notfallmed. 1988 Aug;23(4):217-9.

PMID:3052154
Abstract

In view of repeated communications in recent years reporting on lethal infusions of fructose or sorbitol in adults with hereditary fructose intolerance, the known statements on the incidence of 1:20,000 are critically analysed. The validity is relativated. The special indication for sorbitol as an osmotherapeutic preparation for lowering intracranial pressure is pointed out. A modified intravenous fructose tolerance test is suggested.

摘要

鉴于近年来有多次关于遗传性果糖不耐受成人因输注果糖或山梨醇致死的报道,对已知的发病率为1:20000的说法进行了批判性分析。其有效性受到质疑。指出了山梨醇作为降低颅内压的渗透治疗制剂的特殊适应症。建议采用改良的静脉果糖耐量试验。

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