Suppr超能文献

一种基于自我中心数据估计家庭内部接触网络的惩罚似然方法。

A penalized likelihood approach to estimate within-household contact networks from egocentric data.

作者信息

Potter Gail E, Hens Niel

机构信息

California Polytechnic State University, San Luis Obispo, CA, U.S.A., Center for Statistics and Quantitative Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, WA, U.S.A.

出版信息

J R Stat Soc Ser C Appl Stat. 2013 Aug 1;62(4):629-648. doi: 10.1111/rssc.12011.

Abstract

Acute infectious diseases are transmitted over networks of social contacts. Epidemic models are used to predict the spread of emergent pathogens and compare intervention strategies. Many of these models assume equal probability of contact within mixing groups (homes, schools, etc.), but little work has inferred the actual contact network, which may influence epidemic estimates. We develop a penalized likelihood method to infer contact networks within households, a key area for disease transmission. Using egocentric surveys of contact behavior in Belgium, we estimate within-household contact networks for six different age compositions. Our estimates show dependency in contact behavior and vary substantively by age composition, with fewer contacts occurring in older households. Our results are relevant for epidemic models used to make policy recommendations.

摘要

急性传染病通过社会接触网络传播。流行病模型用于预测新出现病原体的传播并比较干预策略。这些模型中的许多都假设在混合群体(家庭、学校等)内接触的概率相等,但很少有研究推断实际的接触网络,而这可能会影响疫情估计。我们开发了一种惩罚似然方法来推断家庭内部的接触网络,这是疾病传播的一个关键领域。利用对比利时接触行为的自我中心调查,我们估计了六种不同年龄构成家庭内部的接触网络。我们的估计结果显示了接触行为中的依赖性,并且因年龄构成而有很大差异,老年家庭中的接触较少。我们的结果对于用于制定政策建议的流行病模型具有参考价值。

相似文献

7
Epidemic spread on weighted networks.加权网络上的疫情传播。
PLoS Comput Biol. 2013;9(12):e1003352. doi: 10.1371/journal.pcbi.1003352. Epub 2013 Dec 12.

本文引用的文献

4
The transmissibility and control of pandemic influenza A (H1N1) virus.大流行性流感 A(H1N1)病毒的传播和控制。
Science. 2009 Oct 30;326(5953):729-33. doi: 10.1126/science.1177373. Epub 2009 Sep 10.
5
Spread of infectious disease through clustered populations.传染病在聚集人群中的传播。
J R Soc Interface. 2009 Dec 6;6(41):1121-34. doi: 10.1098/rsif.2008.0524. Epub 2009 Mar 4.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验