Bove A, Papanikolaou Ig, Bongarzoni G, Mattei Pa, Markogiannakis H, Chatzipetrou M, D'Addetta V, Di Renzo Rm, Fiordaliso M, Corbellini L
Department of Surgical Sciences, Medical School, University of Chieti-Pescara, Chieti, Italy.
Hippokratia. 2012 Apr;16(2):154-9.
New surgical technologies have been introduced in thyroid surgery, to achieve vessel sealing and hemostasis. The aim of the study was to examine their effectiveness and compare the outcome of total thyroidectomy using the Harmonic Focus™, the LigaSure® Precise and the conventional technique of suture ligation.
A retrospective case-matched study of all total thyroidectomies between October 2008 through May 2010 was conducted. Patients (n=240) underwent total thyroidectomy using three different methods; the Harmonic Focus™ (Group F, n=80), the LigaSure Precise® (Group L, n=80) and the conventional technique of suture ligation (Group C, n=80).
No significant differences were identified between the 3 groups in terms of demographics, thyroid gland weight, pathologic diagnosis, preoperative and postoperative calcium levels, postoperative complications, duration of hospital stay, and final outcome. The operative time was shorter with Harmonic Focus® by about 15%. Statistical analysis revealed a statistically significant difference between operations with F (62.7±14.1 minutes) and C (72.7±13.6minutes) with (p=0.019).
Both devices were safe and efficient. A significant reduction of the operative time was found with Harmonic Focus® compared to the other two techniques with no statistically significant differences in postoperative complications in the 3 groups.
甲状腺手术中引入了新的手术技术，以实现血管封闭和止血。本研究的目的是检验其有效性，并比较使用Harmonic Focus™、LigaSure® Precise和传统缝线结扎技术进行甲状腺全切除术的结果。
对2008年10月至2010年5月期间所有甲状腺全切除术进行回顾性病例对照研究。患者（n = 240）采用三种不同方法进行甲状腺全切除术；Harmonic Focus™（F组，n = 80）、LigaSure Precise®（L组（L组，n = 80）和传统缝线结扎技术（C组，n = 80）。
三组在人口统计学、甲状腺重量、病理诊断、术前和术后钙水平、术后并发症、住院时间和最终结果方面未发现显著差异。Harmonic Focus®的手术时间缩短了约15%。统计分析显示，F组（62.7±14.1分钟）和C组（72.7±13.6分钟）的手术之间存在统计学显著差异（p = 0.019）。
两种器械均安全有效。与其他两种技术相比，Harmonic Focus®的手术时间显著缩短，三组术后并发症无统计学显著差异。
