Huang Y, Feng J F
Nursing Department, Zhejiang Cancer Hospital, Hangzhou, China.
Hippokratia. 2013 Jan;17(1):68-72.
Solid pseudopapillary tumor (SPT) of the pancreas is a very rare neoplasm of low malignant potential that mostly affects young women. The aim of the present study is to report our experience in surgical treatment of SPT and review of the literature.
A retrospective review of three cases of SPT who were treated at our department during the last two years was performed. The clinicopathologic characteristics, surgical treatment, and prognosis are described in detail.
Case 1 described an asymptomatic SPT in a pregnant woman. To the best of our knowledge, only one case of SPT in pregnancy has been reported in the literature. Case 2 described an SPT in the pancreatic tail causing splenic infarction, and a distal pancreatectomy combined with splenectomy was performed. Case 3 described an SPT in the pancreatic head, for which a pancreatoduodenectomy was successfully performed. All of the three patients were followed up for 10-22 months without recurrence or metastases after the initial surgery at the time of reporting.
At present, radical resection is the treatment of choice for SPT. Enucleation can be performed for tumors with complete amicula. Distal pancreatectomy combined with or without splenectomy can be performed for pancreatic body and/or tail tumor, and pancreatoduodenectomy for pancreatic head tumor. The prognosis of SPT is good.
胰腺实性假乳头状瘤（SPT）是一种非常罕见的、恶性潜能低的肿瘤，主要影响年轻女性。本研究的目的是报告我们在SPT手术治疗方面的经验并进行文献复习。
对过去两年在我科接受治疗的3例SPT患者进行回顾性分析。详细描述了其临床病理特征、手术治疗及预后情况。
病例1为一名孕妇的无症状SPT。据我们所知，文献中仅报道过1例妊娠期SPT。病例2为胰腺尾部的SPT导致脾梗死，行远端胰腺切除术联合脾切除术。病例3为胰头部的SPT，成功实施了胰十二指肠切除术。在报告时，所有3例患者在初次手术后均随访了10 - 22个月，无复发或转移。
目前，根治性切除是SPT的首选治疗方法。对于包膜完整的肿瘤可进行剜除术。对于胰体和/或胰尾肿瘤可施行远端胰腺切除术联合或不联合脾切除术，对于胰头部肿瘤可行胰十二指肠切除术。SPT的预后良好。
