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母羊超营养水平硒及营养状况对后代甲状腺激素和皮质醇浓度的影响

Thyroid Hormones and Cortisol Concentrations in Offspring are Influenced by Maternal Supranutritional Selenium and Nutritional Plane in Sheep.

作者信息

Vonnahme Kimberly A, Neville Tammi L, Lekatz Leslie A, Reynolds Lawrence P, Hammer Carolyn J, Redmer Dale A, Caton Joel S

机构信息

Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University, Fargo, ND, USA.

出版信息

Nutr Metab Insights. 2013 Apr 17;6:11-21. doi: 10.4137/NMI.S11332. Print 2013.

DOI:10.4137/NMI.S11332
PMID:23935368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3735671/
Abstract

To determine the effects of maternal supranutritional selenium (Se) supplementation and maternal nutritional plane on offspring growth potential, ewes were randomly assigned to 1 of 6 treatments in a 2 × 3 factorial arrangement [dietary Se (adequate Se; 9.5 μg/kg body weight vs. high Se; 81.8 μg/kg body weight initiated at breeding) and plane of nutrition [60%, 100%, or 140% of requirements; initiated on day 50 of gestation]]. Lambs were immediately removed from dams at birth and reared. Cortisol concentrations at birth were similar, but by 24 h, a relationship (P = 0.02) between maternal Se supplementation and nutritional plane on cortisol concentrations was observed in lambs. A sex of offspring × day of age interaction (P = 0.01) and a maternal Se supplementation × nutritional plane × day of age interaction (P = 0.04) was observed for thyroxine concentrations. Differences in growth may be influenced by thyroid hormone production early in neonatal life.

摘要

为了确定母羊超营养水平补充硒(Se)以及母羊营养水平对后代生长潜力的影响,将母羊按照2×3析因设计随机分为6种处理之一[日粮硒(充足硒;繁殖时开始为9.5μg/kg体重,高硒;繁殖时开始为81.8μg/kg体重)和营养水平[需求量的60%、100%或140%;妊娠第50天开始]]。羔羊出生时立即与母羊分离并进行饲养。出生时皮质醇浓度相似,但到24小时时,观察到母羊补充硒和营养水平与羔羊皮质醇浓度之间存在关系(P = 0.02)。观察到甲状腺素浓度存在后代性别×日龄交互作用(P = 0.01)以及母羊补充硒×营养水平×日龄交互作用(P = 0.04)。生长差异可能受新生期早期甲状腺激素产生的影响。

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