Kortequee S, Karkos P D, Atkinson H, Sethi N, Sylvester D C, Harar R S, Sood S, Issing W J
Department of Otolaryngology, Bradford Royal Infirmary, Bradford BD9 6RJ, UK.
Int J Otolaryngol. 2013;2013:946780. doi: 10.1155/2013/946780. Epub 2013 Jul 11.
Globus pharyngeus is a common ENT condition. This paper reviews the current evidence on globus and gives a rational guide to the management of patients with globus. The aetiology of globus is still unclear though most ENT surgeons believe that reflux whether acidic or not plays a significant role. Though proton pump inhibitors are used extensively in practice, there is little evidence to support their efficacy. Most patients with globus can be discharged after simple office investigations. The role of pepsin-induced laryngeal injury is an exciting concept that needs further study. Given the benign nature of globus pharyngeus, in most cases, reassurance rather than treatment or extensive investigation with rigid oesophagoscopy or contrast swallows is all that is needed. We need more research into the aetiology of globus.
咽异感症是一种常见的耳鼻喉科疾病。本文回顾了关于咽异感症的现有证据，并为咽异感症患者的管理提供合理指导。尽管大多数耳鼻喉科外科医生认为反流（无论是否为酸性）起着重要作用，但咽异感症的病因仍不明确。虽然质子泵抑制剂在实践中被广泛使用，但几乎没有证据支持其疗效。大多数咽异感症患者在进行简单的门诊检查后即可出院。胃蛋白酶引起的喉损伤这一概念令人兴奋，需要进一步研究。鉴于咽异感症的良性性质，在大多数情况下，只需给予安慰，而无需进行治疗或通过硬质食管镜检查或造影吞咽进行广泛检查。我们需要对咽异感症的病因进行更多研究。
