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血小板减少症在严重烧伤患者中引发多发性颅内出血:16例病例回顾

Thrombocytopenia induces multiple intracranial hemorrhages in patients with severe burns: A review of 16 cases.

作者信息

Zhou Jianda, Liu Jinyan, Luo Chengqun, Hu Feng, Liu Rui, Chen Zizi, Chen Yao, Xiong Wu, Xie Jianfei, He Quanyong, Yin Chaoqi, Wang Shaohua, Zhang Yanwen, Zeng Sainan

机构信息

The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.

出版信息

Exp Ther Med. 2013 Jul;6(1):223-227. doi: 10.3892/etm.2013.1081. Epub 2013 Apr 29.

Abstract

The aim of this study was to explore the etiology and diagnosis of multiple intracranial hemorrhages (ICHs) following severe burns, with a retrospective review of 16 cases of severe burns further complicated by multiple ICHs. Using cranial CT scans of the brains, we identified that all patients presented with low platelet counts and coagulation abnormalities prior to intracranial hemorrhaging. Following conventional treatment and various supporting treatments, five cases succumbed following a progressive reduction in blood platelet levels and the ICHs were cured in 11 cases following the restoration of normal platelet levels. We conclude that low platelet counts and coagulation abnormalities may cause multiple ICHs following severe burns and early diagnosis and treatment is the key to successful treatment.

摘要

本研究旨在探讨重度烧伤后多发性颅内出血(ICH)的病因及诊断,回顾性分析16例重度烧伤并发多发性ICH的病例。通过脑部CT扫描,我们发现所有患者在颅内出血前均出现血小板计数低和凝血异常。经过常规治疗和各种支持治疗,5例患者因血小板水平逐渐下降而死亡,11例患者在血小板水平恢复正常后ICH得到治愈。我们得出结论,血小板计数低和凝血异常可能导致重度烧伤后多发性ICH,早期诊断和治疗是成功治疗的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2190/3735512/5224df4f69d1/ETM-06-01-0223-g00.jpg

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