Department of Urology, Medical University of Graz (MUG), Graz, Austria.
Biomed Res Int. 2013;2013:957547. doi: 10.1155/2013/957547. Epub 2013 Jul 14.
To evaluate the impact of SPARC on female sexual function.
151 women with a mean age of 60 ± 11.90 and SUI had a complete urodynamic investigation and underwent SPARC operation. 98 women completed the validated female sexual function index questionnaire (FSFI) at baseline and 94 women at follow-up. A minimum follow-up of 12 months was required for study inclusion.
52/98 women were sexually active at baseline. Postoperatively only 33 patients were sexually active. The FSFI score of all 33 pre- and postoperative sexually active women increased from 25.3 ± 5.7 at baseline to 27.4 ± 4.8 at follow-up (P = 0.1). Scores of women with reduced sexual function at baseline increased significantly in the domains desire, arousal, and lubrication as well as orgasm and satisfaction and total FSFI-score (P = 0.002) postoperatively.
Our results suggest that the SPARC-sling procedure for SUI did not negatively interfere with female sexual function.
评估基质细胞衍生因子 1（SDF-1）对女性性功能的影响。
对 151 例年龄 60±11.90 岁、有完全尿动力学检查和 SDF-1 手术史的压力性尿失禁（SUI）女性进行了研究。98 例女性在基线时完成了经过验证的女性性功能指数问卷（FSFI），94 例在随访时完成。研究纳入的最低随访时间为 12 个月。
52/98 例女性在基线时有性生活。术后只有 33 例患者有性生活。所有 33 例术前和术后有性生活的女性的 FSFI 评分均从基线时的 25.3±5.7 增加到随访时的 27.4±4.8（P=0.1）。基线时性功能减退的女性在欲望、唤起、润滑以及性高潮和满意度以及总 FSFI 评分方面的评分显著增加（P=0.002）。
我们的结果表明，SDF-1 吊带手术治疗 SUI 不会对女性性功能产生负面影响。
