Nilsson C G, Palva K, Rezapour M, Falconer C
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Haartmaninkatu 2, Helsinki, POB 140, 00029 HUS, Finland.
Int Urogynecol J Pelvic Floor Dysfunct. 2008 Aug;19(8):1043-7. doi: 10.1007/s00192-008-0666-z. Epub 2008 Jun 6.
The aim of this study was to evaluate the long-term effectiveness and safety of the tension-free vaginal tape (TVT) procedure. In a Nordic three-center prospective observational cohort study, 90 women with primary stress incontinence had a TVT operation performed in local anesthesia. Assessment included a 24-h pad test, a stress test, physical examination, and a visual analog scale for assessing the degree of bother. Patient's global impression of cure was obtained, and condition specific quality of life questionnaires were used. Seventy-seven percent of the initial cohort of 90 women and 89% of those alive and capable of cooperating were assessed 11.5 years after the TVT operation. Ninety percent of the women had both a negative stress test and a negative pad test being objectively cured. Subjective cure by patients global impression was found in 77%, 20% being improved and only 3% regarded the operation as a failure. No late-onset adverse effects of the operation were found, and no case of tape erosion was seen. The TVT procedure is safe and effective for more than 10 years.
本研究的目的是评估无张力阴道吊带术（TVT）的长期有效性和安全性。在一项北欧三中心前瞻性观察队列研究中，90例原发性压力性尿失禁女性在局部麻醉下接受了TVT手术。评估包括24小时护垫试验、压力试验、体格检查以及用于评估困扰程度的视觉模拟量表。获取患者对治愈的总体印象，并使用特定疾病的生活质量问卷。在TVT手术后11.5年，对最初90例女性队列中的77%以及存活且能够配合的女性中的89%进行了评估。90%的女性压力试验和护垫试验均为阴性，客观上已治愈。根据患者总体印象得出的主观治愈率为77%，20%有所改善，仅3%认为手术失败。未发现手术的迟发性不良反应，也未见到吊带侵蚀病例。TVT手术在10多年的时间里安全有效。
