PPGCA/Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Biomed Res Int. 2013;2013:978256. doi: 10.1155/2013/978256. Epub 2013 Jul 2.
Adsorption of phenolic amino acids, such as phenylalanine and tyrosine, is quite relevant for the production of protein hydrolysates used as dietary formulations for patients suffering from congenital disorders of amino acid metabolism, such as phenylketonuria. In this study, an adsorbent prepared from corn cobs was evaluated for the removal of tyrosine (Tyr) from both a single component solution and a binary aqueous solution with phenylalanine (Phe). The adsorption behavior of tyrosine was similar to that of phenylalanine in single component solutions, however, with a much lower adsorption capacity (14 mg g(-1) for Tyr compared to 109 mg g(-1) for Phe). Tyr adsorption kinetics was satisfactorily described by a pseudosecond-order model as it was for Phe. In adsorption equilibrium studies for binary mixtures, the presence of Tyr in Phe solutions favored Phe faster adsorption whereas the opposite behavior was observed for the presence of Phe in Tyr solutions. Such results indicate that, in binary systems, Phe will be adsorbed preferably to Tyr, and this is a welcome feature when employing the prepared adsorbent for the removal of Phe from protein hydrolysates to be used in dietary formulations for phenylketonuria treatment.
酚性氨基酸（如苯丙氨酸和酪氨酸）的吸附对于用于治疗先天性氨基酸代谢紊乱（如苯丙酮尿症）患者的蛋白质水解产物的生产非常重要。在这项研究中，评估了一种由玉米芯制成的吸附剂，以去除单一成分溶液和包含苯丙氨酸（Phe）的二元水溶液中的酪氨酸（Tyr）。在单一成分溶液中，酪氨酸的吸附行为与苯丙氨酸相似，但吸附容量要低得多（Tyr 为 14mg/g，而 Phe 为 109mg/g）。Tyr 的吸附动力学可以很好地用伪二级模型来描述，就像 Phe 一样。在二元混合物的吸附平衡研究中，Tyr 在 Phe 溶液中的存在有利于 Phe 的快速吸附，而在 Tyr 溶液中存在 Phe 时则观察到相反的行为。这些结果表明，在二元体系中，Phe 将优先吸附到 Tyr 上，当使用制备的吸附剂从用于治疗苯丙酮尿症的饮食配方的蛋白质水解产物中去除 Phe 时，这是一个受欢迎的特性。
