Ministry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an, Shaanxi 710069, PR China.
Org Lett. 2013 Sep 6;15(17):4334-7. doi: 10.1021/ol401795m. Epub 2013 Aug 12.
A novel rhodamine based probe with a unique six-membered spirocycle was rationally designed for detection of Hg(2+) with greatly improved selectivity, sensitivity, and photostability. The probe has been shown to be suitable for Hg(2+) imaging in living cells and mapping Hg(2+) distribution in living cell-EPS-mineral aggregates under anoxic conditions.
一种新型基于罗丹明的探针，具有独特的六元螺环，被合理设计用于检测 Hg(2+)，具有大大提高的选择性、灵敏度和光稳定性。该探针已被证明适用于活细胞中的 Hg(2+)成像以及在缺氧条件下活细胞-EPS-矿物聚集体中 Hg(2+)分布的映射。
