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[环境颗粒物(PM10)对脑血管疾病人群死亡率的影响——一项病例交叉研究]

[The impact of ambient particulate matter (PM10) on the population mortality for cerebrovascular diseases-a case-crossover study].

作者信息

Wang Xu-ying, Dong Feng-ming, Jin Ming-hao, Pan Xiao-chuan

机构信息

Department of Occupational and Environmental Health, School of Public Health, Peking University, Beijing 100191, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Apr;34(4):331-5.

PMID:23937835
Abstract

OBJECTIVE

To analyze the association between the concentration of ambient inhalable particulate matter (PM10) and population mortality for cerebrovascular diseases and to explore the impact of PM10 on cerebrovascular diseases.

METHODS

Data including meteorological factors, air pollutants (NO2, SO2 and PM10) and cerebrovascular disease mortality in one district of Beijing from 2004 to 2008 were collected and both symmetric bidirectional case-crossover design and conditional logistic regression model were used to analyze the associations among them.

RESULTS

After adjusting the influence of meteorological factors as daily average temperature and relative humidity, the single pollutant model showed that there was no significant lag effect. In the multi-pollutant model, the effect of the every 105.43 µg/m(3) increase of ambient PM10 had a larger impact on the daily death of the cerebrovascular diseases with statistically significant difference (P < 0.05). The effect of ambient PM10 pollution on daily death of cerebrovascular diseases was significant for females, 65 year-olds and in winter season.

CONCLUSION

Our data showed that elevated levels of ambient PM10 was positively associated with the increase of cerebrovascular disease mortality. The elevated levels of ambient PM10 could lead to the increase of the daily mortality on cerebrovascular diseases for females, elderly who were 65 or older and in winter seasons.

摘要

目的

分析环境空气中可吸入颗粒物(PM10)浓度与脑血管疾病人群死亡率之间的关联,并探讨PM10对脑血管疾病的影响。

方法

收集2004年至2008年北京市某区的气象因素、空气污染物(二氧化氮、二氧化硫和PM10)及脑血管疾病死亡率等数据,采用对称双向病例交叉设计和条件logistic回归模型分析它们之间的关联。

结果

在调整日平均气温和相对湿度等气象因素的影响后,单污染物模型显示无明显滞后效应。在多污染物模型中,环境PM10每增加105.43μg/m³对脑血管疾病日死亡人数的影响更大,差异有统计学意义(P<0.05)。环境PM10污染对脑血管疾病日死亡人数的影响在女性、65岁及以上人群和冬季较为显著。

结论

我们的数据表明,环境PM10水平升高与脑血管疾病死亡率增加呈正相关。环境PM10水平升高可导致女性、65岁及以上老年人和冬季脑血管疾病日死亡人数增加。

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