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中国北京大气颗粒物与脑血管疾病急诊就诊之间的关联。

Association between atmospheric particulate matter and emergency room visits for cerebrovascular disease in Beijing, China.

作者信息

Cheng Bowen, Zhou Jianding, Ma Yuxia, Zhang Yifan, Wang Hang, Chen Yan, Shen Jiahui, Feng Fengliu

机构信息

College of Atmospheric Sciences, Key Laboratory of Semi-Arid Climate Change, Ministry of Education, Lanzhou University, Lanzhou, 730000 China.

Quanzhou Meteorological Bureau, Quanzhou, 362000 China.

出版信息

J Environ Health Sci Eng. 2022 Jan 8;20(1):293-303. doi: 10.1007/s40201-021-00776-w. eCollection 2022 Jun.

DOI:10.1007/s40201-021-00776-w
PMID:35669822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9163215/
Abstract

PURPOSE

The association between atmospheric particulate matter and emergency room visits for cerebrovascular disease were evaluated in Beijing.

METHODS

A generalized additive model was used to evaluate the associations between particulate matter and cerebrovascular disease, based on the daily data of meteorological elements, PM concentrations, and emergency room (ER) visits for cerebrovascular disease in Beijing from 2009 to 2012. Long-term trends and the effects of holidays, the day of the week, and confounding factors were controlled to determine the lag effect at 0-6 days. Single- and double-pollutant models were employed for different age and sex groups.

RESULTS

The effect of PM concentration on the number of daily ER visits for cerebrovascular disease was much stronger than that of PM concentration. PM and PM had maximum RR values of 1.096 and 1.054 at lag 6 for patients aged 61-75 years. For each inter-quartile range (IQR) increase in PM concentration, the maximum RR values for the total, males, females, aged 15-60 years, aged 61-75 years, and aged > 75 years were 1.024, 1.044, 1.043, 1.038, 1.054, and 1.032, respectively. For each IQR increase in PM concentration, the maximum RR values for the total, males, females, aged 15-60 years, aged 61-75 years, and aged > 75 years were 1.038, 1.064, 1.076, 1.054, 1.096, and 1.049, respectively. The RR values of the double-pollutant models were lower than those of the single-pollutant models.

CONCLUSION

This study showed that the effects of PM pollution on cerebrovascular disease were different among different gender and age groups, and aged 61-75 years were mostly sensitive to particulate matters. The effects of PM on cerebrovascular disease were stronger than those of PM. Our results can provide scientific evidence for the local government to take effective measures to improve air quality and the health of residents.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s40201-021-00776-w.

摘要

目的

评估北京大气颗粒物与脑血管疾病急诊就诊之间的关联。

方法

基于2009年至2012年北京的气象要素、PM浓度及脑血管疾病急诊就诊的每日数据,采用广义相加模型评估颗粒物与脑血管疾病之间的关联。控制长期趋势、节假日、星期几及混杂因素的影响,以确定0至6天的滞后效应。针对不同年龄和性别组采用单污染物和双污染物模型。

结果

PM浓度对脑血管疾病每日急诊就诊次数的影响远强于PM浓度的影响。对于61至75岁的患者,PM和PM在滞后6天时的最大RR值分别为1.096和1.054。PM浓度每增加一个四分位间距(IQR),总体、男性、女性、15至60岁、61至75岁及75岁以上人群的最大RR值分别为1.024、1.044、1.043、1.038、1.054和1.032。PM浓度每增加一个IQR,总体、男性、女性、15至60岁、61至75岁及75岁以上人群的最大RR值分别为1.038、1.064、1.076、1.054、1.096和1.049。双污染物模型的RR值低于单污染物模型。

结论

本研究表明,PM污染对脑血管疾病的影响在不同性别和年龄组中存在差异,61至75岁人群对颗粒物最为敏感。PM对脑血管疾病的影响强于PM。我们的结果可为当地政府采取有效措施改善空气质量和居民健康提供科学依据。

补充信息

在线版本包含可在10.1007/s40201-021-00776-w获取的补充材料。

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