Department of Anesthesiology, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.
Med Hypotheses. 2013 Oct;81(4):707-12. doi: 10.1016/j.mehy.2013.07.033. Epub 2013 Aug 9.
Ketorolac, a NSAID routinely used during surgery proposed to have anticancer effects, is a promising way to improve postoperative oncological outcome. This effect may be particularly prominent in patients with elevated preoperative inflammatory scores, like the neutrophil:lymphocyte ratio. In this paper, we describe the rationale, the preliminary analyses in our patients, the feasibility and the methodology of a prospective randomized trial called "Ketorolac in Breast Cancer trial" (KBCt) (NCT01806259).
酮咯酸，一种常用于手术的 NSAID，据报道具有抗癌作用，是改善术后肿瘤学结果的一种很有前途的方法。这种作用在术前炎症评分升高的患者中可能更为显著，如中性粒细胞与淋巴细胞比值。本文描述了一项名为“乳腺癌中酮咯酸试验”（KBCt）的前瞻性随机试验的原理、初步分析、可行性和方法（NCT01806259）。
