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一项关于心脏康复患者对服药看法的定性研究:对“药物抵抗”服药模式的启示。

A qualitative study of cardiac rehabilitation patients' perspectives on taking medicines: implications for the 'medicines-resistance' model of medicine-taking.

机构信息

School of Pharmacy, Keele University, Staffordshire ST5 5BG, UK.

出版信息

BMC Health Serv Res. 2013 Aug 9;13:302. doi: 10.1186/1472-6963-13-302.

Abstract

BACKGROUND

The appropriate use of medicines continues to be an important area of inter-disciplinary research activity both in the UK and beyond. Key qualitative work in this area in the last decade has included the 'medicines resistance' model of medicine-taking, which was based on a meta-ethnography of 37 qualitative studies. This model proposed that patients approach medicine-taking as 'passive accepters', 'active accepters', 'active modifiers' or 'complete rejecters', of which the latter two categories were considered to show 'resistance' to medicines. However, critical assessment of the model appears to be currently lacking, particularly in terms of its use in clinical practice. This paper seeks to contribute to the literature in this area by critically examining the practical application of the model in light of the findings from a qualitative, follow-up study of cardiac rehabilitation patients' perspectives and experiences of using medicines.

METHODS

Following ethical approval, in-depth, audiotaped, qualitative interviews were conducted with fifteen patients who had completed a UK hospital-based cardiac rehabilitation programme. Participants were aged 42-65, white British and from a variety of socioeconomic backgrounds. Interview topics included perspectives on coronary heart disease, medicine-taking and lifestyle changes. Follow-up interviews with ten patients approximately nine months later explored whether their perspectives had changed.

RESULTS

The findings suggest that the active/passive and accepter/modifier distinctions may not allow for clear determination of which profile a patient fits into at any given point, and that definitions such as 'accepter' and 'resistance' may be insufficiently discerning to categorise patients' use of medicines in practice. These problems appear to arise when the issue of patients' accounts about medicines adherence are considered, since patients may have concerns or disquiet about medicines whether or not they are adherent and the model does not consider disquiet in isolation from adherence.

CONCLUSIONS

Practical application of the 'medicines resistance' model of medicine-taking may be problematic in this patient group. Dissociation of disquiet about medicines from medicines adherence may allow for a focus on helping patients to resolve their disquiet, if possible, without this necessarily having to be viewed in terms of its potential effect on adherence.

摘要

背景

在英国和其他国家,药物的合理使用仍然是跨学科研究活动的一个重要领域。在过去十年中,该领域的关键定性工作包括基于 37 项定性研究的元人种学的“药物抵抗”模型。该模型提出,患者将用药视为“被动接受者”、“主动接受者”、“主动调整者”或“完全拒绝者”,后两者被认为对药物表现出“抵抗”。然而,目前似乎缺乏对该模型的批判性评估,特别是在其在临床实践中的应用方面。本文旨在通过批判性地审视该模型在定性随访研究中对心脏康复患者用药观点和经验的实际应用,为该领域的文献做出贡献。

方法

在获得伦理批准后,对 15 名完成英国医院心脏康复计划的患者进行了深入的、录音的定性访谈。参与者年龄在 42-65 岁之间,是白人英国人和来自各种社会经济背景的人。访谈主题包括对冠心病、用药和生活方式改变的观点。大约九个月后对 10 名患者进行了随访访谈,探讨他们的观点是否发生了变化。

结果

研究结果表明,主动/被动和接受者/调整者的区别可能无法明确确定患者在任何特定时间属于哪种类型,而“接受者”和“抵抗”等定义可能不足以区分患者在实践中用药的情况。这些问题似乎出现在考虑患者关于药物依从性的报告时,因为无论患者是否遵守药物治疗,他们都可能对药物有担忧或不满,而该模型并未将不满与依从性分开考虑。

结论

在该患者群体中,“药物抵抗”模型的实际应用可能存在问题。将对药物的不满与药物依从性分开,可能有助于关注帮助患者解决他们的不满,如果可能的话,而无需将其视为对依从性的潜在影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a148/3750914/599f64d139be/1472-6963-13-302-1.jpg

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