School of Pharmacy, College of Medical and Dental Sciences, Sir Robert Aitken Institute for Medical Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
School of Pharmacy and Life Sciences, Robert Gordon University, Riverside East, Garthdee Road, Aberdeen, AB10 7GJ, UK.
Public Health. 2017 Jul;148:1-8. doi: 10.1016/j.puhe.2017.03.002. Epub 2017 Mar 31.
This study aimed to explore behavioural determinants of homeless patients' adherence to prescribed medicines using Theoretical Domains Framework (TDF).
A qualitative study using semi-structured, face-to-face interviews.
Participants were recruited from a homelessness primary healthcare centre in Aberdeen, United Kingdom (UK). Face-to-face interviews were audio-recorded and transcribed verbatim. Thematic analysis of the interview data was conducted using the Framework Approach based on the Theoretical Domains Framework. National Health Service ethical and Research and Development (R&D) approval was obtained.
Twenty-five patients were interviewed, at which point data saturation was achieved. A total of 13 out of 14 Theoretical Domains Framework domains were identified that explained the determinants of adherence or non-adherence to prescribed medicines. These included: 'beliefs about consequences' (e.g. non-adherence leading to poor health); 'goals' of therapy (e.g. being a 'normal' person with particular reference to methadone adherence); and 'environmental context and resources' (e.g. stolen medicines and the lack of secure storage). Obtaining food and shelter was higher priority than access and adherence to prescribed medicines while being homeless.
Behavioural determinants of non-adherence identified in this study were mostly related to participants' homelessness and associated lifestyle. Results are relevant to developing behaviour change interventions targeting non-adherent homeless patients and to the education of healthcare professionals serving this vulnerable population.
本研究旨在使用理论域框架(TDF)探讨无家可归患者遵医嘱服药的行为决定因素。
这是一项使用半结构式面对面访谈的定性研究。
参与者从英国阿伯丁的一个无家可归者初级保健中心招募。对面对面访谈进行录音并逐字转录。使用基于理论域框架的框架方法对访谈数据进行主题分析。英国国民保健制度(NHS)和研究与开发(R&D)部门均批准了该研究。
共对 25 名患者进行了访谈,此时达到了数据饱和。共有 14 个理论域框架域中的 13 个被确定为解释遵医嘱或不遵医嘱服药的决定因素。这些因素包括:“对后果的信念”(例如,不遵医嘱会导致健康状况不佳);“治疗目标”(例如,成为一个“正常”的人,特别是在坚持美沙酮方面);以及“环境背景和资源”(例如,药物被盗和缺乏安全储存)。无家可归时,获得食物和住所比获得和遵医嘱服药更重要。
本研究确定的不遵医嘱行为决定因素主要与参与者的无家可归状况及其相关生活方式有关。研究结果与为非遵医嘱的无家可归患者制定行为改变干预措施以及为服务这一弱势群体的医疗保健专业人员提供教育相关。